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TP53 BRCA1 CRISPR single-cell cancer

Pommier(Yves),Sun(Yilun),Huang(Shar-Yin N)... Nat Rev Mol Cell Biol 0000-00-00

...TOP1, TOP1mt, TOP2α, TOP2β, TOP3α and TOP3β), which act on a broad range of DNA and RNA substrates at the nuclear and mi...

Subhash(Vinod Vijay),Tan(Shi Hui),Yeo(Mei ... Mol Cancer Ther 0000-00-00

...TOP1 inhibitors, veliparib (ABT-888) and irinotecan (CPT-11), respectively. ATM expression was detected in a panel of ga...

Nagy(Ádám),Pongor(Lőrinc Sándor),Szabó(And... Int J Cancer 0000-00-00

...TOP1, PEX3 and ABL2. The KRAS signature had a high prognostic power. Similar results were achieved when using the second...

Li(Min),Liu(Yilun) Genomics Proteomics Bioinfo... 0000-00-00

...TOP1) is an essential enzyme for normal development. TOP1 relaxes supercoiled DNA to remove helical constraints that can...

Bennett(Ryan P),Stewart(Ryan A),Hogan(Pris... Antiviral Res 0000-00-00

...TOP1). CPT analogs also have anti-HIV-1 (HIV) activity that was previously shown to be independent of TOP1 inhibition. W...

D'Alfonso(Anna),Di Felice(Francesca),Carli... J Mol Biol 0000-00-00

...top1Δ cells with yeast, human, truncated, and chimeric yeast/human TOP1 constructs and of assessing the extent of non-co...

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