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RNA-seq of LPS-challenged microglial cell treatment with TOP1 inhibitor

样本量:9 物种:Mus musculus, Mus musculus 类型:RNA-seq of coding RNA 2022年4月27日

...TOP1 inhibitor topotecan (TPT)'s role of anti-inflammation in microglial. RNA from mouse microgial cells, cells with LPS...

Ligand-Dependent Enhancer Activation Regulated by Topoisomerase-I Activity

样本量:26 物种:Homo sapiens 类型:other, ChIP-seq, RNA-seq of coding RN... 2015年1月22日

...TOP1) to a large cohort of AR-regulated enhancers. Furthermore, we show that the DNA nicking activity of TOP1 is a prere...

microRNA profiling by array to identify Camptothecin induced modification of ...

样本量:8 物种:Homo sapiens 类型:microRNA profiling by array 2013年12月2日

...Top1 inhibition and human HIF-1alpha protein regulation and activity, widening the biological and molecular activity of ...

Genome-Wide Transcriptional Effects of the Anti-Cancer Agent Camptothecin

样本量:9 物种:Homo sapiens 类型:RNA-seq of coding RNA 2013年10月29日

The anti-cancer drug camptothecin inhibits replication and transcription by trapping DNA topoisomerase I (Top1) covalent...

Genome-wide cheater screen reveals safeguards for cell cooperation during emb...

样本量:8 物种:Mus musculus 类型:transcription profiling by array 2013年10月21日

...Top1 or p53) and mock embryonic stem cells and collected mRNA on day 4 of coculture, while cells were in the growth phas...

Co-ordinate inhibition of autism candidate genes by topoisomerase inhibitors ...

样本量:14 物种:Homo sapiens, Mus musculus 类型:ChIP-seq, RNA-seq of coding RNA 2013年8月30日

...Top1) and Topoisomerase 2 (Top2) enzymes on mouse cortical neurons. We find that topoisomerases selectively inhibit long...

Co-ordinate inhibiton of autism candidate genes by topoisomerase inhibitors [...

样本量:56 物种:Mus musculus 类型:transcription profiling by array 2013年8月30日

...Top1) and Topoisomerase 2 (Top2) enzymes on mouse cortical neurons. We find that topoisomerases selectively inhibit long...

Transcription poisoning by topoisomerase I is controlled by gene length, spli...

样本量:15 物种:Homo sapiens 类型:transcription profiling by array 2013年4月17日

...Top1 cleavage complexes (Top1cc) up- and down-stream of transcription complexes. However, Top1cc can also be trapped by ...

Topoisomerase I cleavage complexes preferentially down-regulate ubiquitin- an...

样本量:7 物种:Homo sapiens 类型:transcription profiling by array 2013年4月17日

...Top1 cleavage complexes (Top1cc) up- and down-stream of transcription complexes. However, Top1cc can also be trapped by ...

DNA topoisomerase III localizes to centromeres and affects centromeric CENP-A...

样本量:8 物种:Schizosaccharomyces pombe 类型:transcription profiling by tiling arr... 2013年3月14日

...Top1 and Top2 is highly enriched at centromeric central domains, demonstrating that Top3 is the major topoisomerase in t...

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