...CRISPR-Cas9 system was used to introduce double-strand breaks (DSBs), HR efficiency was dramatically increased to 16%, a...
...CRISPR/AsCas12f1 genome editing system and applied systematic metabolic engineering to boost A40926B0 biosynthesis. Firs...
...CRISPR-Cas9 system, marking the first successful application of this technology in the genus Hafnia. Moreover, the adiA ...
...CRISPR-edited cells, and LCP1+/L362F mice replicate these defects. Mechanistically, mutant LCP1 hyper-bundles F-actin, i...
...CRISPR-Cas9, can trigger a copy-paste-type HR event; however, CRISPR-Cas9 more frequently induces imprecise non-homologo...
...CRISPR screening with joint transcriptomic and chromatin readouts has been limited by inefficient recovery of gRNAs from...
...CRISPR-based gene editing technologies holds promise for screening new therapies at scale in vitro. A critical roadblock...
...CRISPR/Cas9-generated LRRK2G2019S/G2019S knock-in cells, we discovered increased sensitivity to oxidative and alkylating...
...CRISPR screens, we identified components of the ULK1 and PIK3C3 complexes for autophagy initiation complexes among the t...
...CRISPR-engineered into C57BL/6J mice, which confirmed the Tuba4a Q176P variant as the causative mutation. Mutant mice ar...
山东省济南市章丘区文博路2号
齐鲁师范学院 genelibs生信实验室
山东省济南市高新区舜华路750号
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