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Therapeutic potential and underlying mechanisms of engineered young plasma-de...

Chen(H),Si(Y),Cheng(Q),Yu(Q),Cui(Z),Yu(S),... Bioact Mater 2027-01-00

...single-cell transcriptomic profiling further revealed that RVG-EXOs not only increased neuronal proportion and modulated...

Unlocking raw-corncob consolidated bioprocessing for malic acid production by...

Zhang(Y),Zhang(Y),Han(L),Liu(J),Liu(D),Sun... Synth Syst Biotechnol 2027-03-00

l-Malic acid is an important C4 platform chemical, but its direct production from raw lignocellulosic biomass by consoli...

Self-powered photothermal-thermoelectric bioelectronic dressings combined wit...

Yuan(X),Shi(J),Zhang(Y),Ding(M),Zhang(Y),L... Biomaterials 2027-01-00

...single-cell RNA sequencing confirm the dressing effectively eradicates Staphylococcus aureus infection, accelerates re-e...

Engineered senescence-targeting apoptotic extracellular vesicles-laden inject...

Shi(P),Yang(ZR),Wu(W),Cheng(Z),Gao(H),Chen... Biomaterials 2027-01-00

As the rapid growth of aging population, intervertebral disc degeneration (IVDD) becomes a prevalent degenerative disord...

Gut-derived macrophages as endogenous carriers for brain-targeted cisplatin n...

Gong(Y),Yan(J),Yang(Y),Zhou(Z),Chen(A),Du(... Biomaterials 2027-01-00

...Single-cell transcriptomic analyses of human and murine CNSL samples revealed a previously unrecognized enrichment of in...

scYeast: a biological-knowledge-guided foundation model on yeast single-cell ...

Fan(X),Liao(W),Xiao(L),Yan(X),Lu(H) Synth Syst Biotechnol 2027-02-00

...single-cell transcriptomics that effectively embeds biological priors. scYeast employs a novel asymmetric parallel archi...

Biomaterials for intervertebral disc regeneration: Niche reprogramming, preci...

Jiang(Y),Li(H),Wang(W),Guo(Q),Wang(C),Li(Y... Bioact Mater 2027-02-00

Intervertebral disc degeneration (IDD) arises from coupled redox imbalance, inflammation, cellular senescence, nutrient ...

Harnessing necroptosis via RIPK1 degradation to potentiate radio-immunotherap...

Wu(T),Lv(B),Wang(H),He(G),Fu(Y),Ji(X),Zeng... Bioact Mater 2027-01-00

...Single-cell RNA sequencing revealed that CC patients exhibiting robust immune responses following radiotherapy (RT) show...

BMP-2-driven osteo-organoid formation retains key osteogenic-support features...

Zhu(F),Ji(L),Wang(J),Liu(C) Bioact Mater 2027-01-00

...Single-cell RNA sequencing further resolved mature B-cell loss and enrichment of inflammatory and mature neutrophil stat...

Dual metabolic checkpoint blockade via a 3D-Printed metalloplatform remodels ...

Meng(X),Liu(Z),Hao(Y),Zhu(Y),Gu(J),Zhong(H... Bioact Mater 2027-02-00

...single-cell analysis, we identified a metabolic division of labor: cancer cells exhibit hyperactive glycolysis, while im...

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