Das(Subhendu K),Rehman(Ishita),Ghosh(Ariji... Nucleic Acids Res 0000-00-00

...Top1 (Top1cc) across the nuclear genome, suggesting Top1-PARylation counteracts CPT-induced stabilization of Top1cc. We ...

Mallepally(Rajender Reddy),Putta(Venkat Re... J Fluoresc 0000-00-00

...TOP1 by using LibDock. Furthermore explore antimicrobial activity, photocleavage and in vitro cytotoxicity assay of four...

Bai(Yang),Li(Liang-Dong),Li(Jun),Lu(Xin) J Ovarian Res 0000-00-00

...TOP1 and TOP2A were found to be correlated to worse OS in all patients and serous patients, but not in endometrioid pati...

Li(Min),Liu(Yilun) Genomics Proteomics Bioinfo... 0000-00-00

...TOP1) is an essential enzyme for normal development. TOP1 relaxes supercoiled DNA to remove helical constraints that can...

Mabb(Angela M),Simon(Jeremy M),King(Ian F)... PLoS One 0000-00-00

...Top1 knockdown, the CRISPR-Cas9 system to delete Top1, TOP1 catalytic inhibitors that do not generate TOP1cc's, and a TO...

Meisenberg(Cornelia),Ashour(Mohamed E),El-... Nucleic Acids Res 0000-00-00

...TOP1) inhibitor irinotecan triggers cell death by trapping TOP1 on DNA, generating cytotoxic protein-linked DNA breaks (...

Bennett(Ryan P),Stewart(Ryan A),Hogan(Pris... Antiviral Res 0000-00-00

...TOP1). CPT analogs also have anti-HIV-1 (HIV) activity that was previously shown to be independent of TOP1 inhibition. W...

D'Alfonso(Anna),Di Felice(Francesca),Carli... J Mol Biol 0000-00-00

...top1Δ cells with yeast, human, truncated, and chimeric yeast/human TOP1 constructs and of assessing the extent of non-co...

Lingzi(Xia),Zhihua(Yin),Xuelian(Li),Yangwu... Oncotarget 0000-00-00

...TOP1) pathway, according to the results from luciferase reporter assays. In conclusion, miR-149 C allele may be a progno...

Harrison(Oliver J),Moorjani(Narain),Torren... PLoS One 0000-00-00

...TOP1, UBC, YWHAZ, and 18S) using geNorm software. The most stable HK genes were found to be GAPDH, UBC and ACTB. Both GA...