Qin(Shang-Yao),Yuan(Yi-Min),Hu(Xin),Sun(Xi... Sheng Li Xue Bao 0000-00-00

...Top1) and type II topoisomerase (Top2), depending on the number of strands cut in one round of action. Top1 induces sing...

Zhang(Yonghong),Zheng(Lanlan),Hong(Jing Ha... Plant Physiol 0000-00-00

...TOP1 is encoded by two paralogous genes (TOP1α and TOP1β), of which TOP1α displays specific developmental functions that...

Meisenberg(Cornelia),Ward(Simon E),Schmid(... J Cancer Sci Ther 0000-00-00

...TOP1) poisons such as irinotecan and topotecan in combination with platinum-based compounds. TOP1 poisons kill cancer ce...

Elsayed(Waheba),El-Shafie(Lamia),Hassan(Mo... Sci Rep 0000-00-00

...TOP1) inhibitor, exhibits anti-tumor activity against a wide range of tumors. Redundancy of TOP1-mediated repair mechani...

Gmeiner(William H),Debinski(Waldemar),Mill... Future Oncol 0000-00-00

...Top1. In this review, the authors provide an overview of the studies that revealed the novel aspects of F10's cytotoxic ...

Cho(Jang-Eun),Huang(Shar-Yin N),Burgers(Pe... Nucleic Acids Res 0000-00-00

...Top1) and are initiated by Top1 incision at the relevant ribonucleotide 3'-phosphodiester. A requirement for the re-liga...

Mabb(Angela M),Simon(Jeremy M),King(Ian F)... PLoS One 0000-00-00

...Top1 knockdown, the CRISPR-Cas9 system to delete Top1, TOP1 catalytic inhibitors that do not generate TOP1cc's, and a TO...

Bai(Yang),Li(Liang-Dong),Li(Jun),Lu(Xin) J Ovarian Res 0000-00-00

...TOP1 and TOP2A were found to be correlated to worse OS in all patients and serous patients, but not in endometrioid pati...

Cho(Jang-Eun),Jinks-Robertson(Sue) J Mol Biol 0000-00-00

...Top1), an enzyme that removes torsional stress that accumulates when DNA strands are separated. Top1 relieves torsional ...

Das(Subhendu K),Rehman(Ishita),Ghosh(Ariji... Nucleic Acids Res 0000-00-00

...Top1 (Top1cc) across the nuclear genome, suggesting Top1-PARylation counteracts CPT-induced stabilization of Top1cc. We ...