Bjornsti(M A),Wang(J C) Proc Natl Acad Sci U S A 1988-02-20

...TOP1 gene or 5'-deletion mutations of it were used to complement the temperature-sensitive phenotype of an E. coli topA ...

Christman(M F),Dietrich(F S),Fink(G R) Cell 1988-12-06

...TOP1 gene (encoding topoisomerase I) or a ts mutation in the TOP2 gene (encoding topoisomerase II) grown at a semipermis...

Brill(S J),DiNardo(S),Voelkel-Meiman(K),St... NCI Monogr 1987-10-22

...top1), including strains with null mutations, are viable and exhibit no obvious growth defects, demonstrating that DNA t...

Brill(S J),DiNardo(S),Voelkel-Meiman(K),St... Nature 1987-04-27

...top1), including strains with null mutations are viable and exhibit no obvious growth defects, demonstrating that DNA to...

Thrash(C),Bankier(A T),Barrell(B G),Sterng... Proc Natl Acad Sci U S A 1985-08-14

...TOP1 is identical to the gene previously called MAK1. Seven top1 (mak1) mutants including gene disruptions are viable, d...

Goto(T),Wang(J C) Proc Natl Acad Sci U S A 1985-12-05

...top1 top2 temperature-sensitive (ts) double mutant and its isogenic top2 ts strain show that, whereas mitotic blocks can...

Uemura(T),Yanagida(M) EMBO J 1984-11-13

...top1) and three endonuclease mutants (end1) were all viable. The double mutant top1 end1 was also viable and, in its ext...

Zengler,Heider,Rossello-Mora,Widdel Arch Microbiol 0000-00-00

...ToP1 were demonstrated in quantitative growth experiments. Strain ToP1 is the first phototrophic bacterium shown to util...

Pommier(Yves),Pourquier(Philippe),Urasaki(... Drug Resist Updat 0000-00-00

...top1) inhibitors (camptothecins and other structurally diverse compounds) are effective and promising anticancer agents....

Baranello(Laura),Kouzine(Fedor),Sanford(Su... Chromosome Res 0000-00-00

...Top1) that is functionally associated with the double helix in vivo, especially with active chromatin, and green fluores...