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Wang(H),Nicholson(P R),Stillman(D J) Mol Cell Biol 1990-05-02

...TOP1. This protein also binds to a site present in the enhancer for the 35S rRNA gene, which is transcribed by RNA polym...

Kim(R A),Wang(J C) J Mol Biol 1989-10-06

...TOP1+ TOP2+, TOP1+ top2 ts, delta top1 TOP2+, and delta top1 top2 ts. Cells synchronized by treatment with the alpha-mat...

Lynn(R M),Bjornsti(M A),Caron(P R),Wang(J ... Proc Natl Acad Sci U S A 1989-06-28

...TOP1 gene encoding the enzyme confirms the essentiality of Tyr-727 for the relaxation of supercoiled DNA by the enzyme. ...

Kim(R A),Wang(J C) Cell 1989-08-03

In a yeast DNA topoisomerase double mutant TG205 (delta top1 top2-4), over half of the rDNA is present as extrachromosom...

Giaever(G N),Wang(J C) Cell 1989-01-04

...top1 top2 ts strains expressing the E. coli enzyme when neither one of the yeast DNA topoisomerases I and II is function...

Eberly(S L),Sakai(A),Sugino(A) Yeast 1989-06-01

...top1' (Thrash et al., 1984). Studies presented here show that the map position of MAK1-3 on chromosome XVI distinguishes...

Brill(S J),Sternglanz(R) Cell 1988-09-08

...top1-top2 ts mutant. Whether this change in linking number is due to an unusual form of topoisomerase II or whether it i...

Yamagishi(M),Nomura(M) Curr Genet 1988-08-24

...top1top2 double mutant. In contrast, no preferential inhibition of rRNA synthesis was observed in top1 or top2 single mu...

Juan(C C),Hwang(J L),Liu(A A),Whang-Peng(J... Proc Natl Acad Sci U S A 1988-12-30

cDNA clones of the human TOP1 gene encoding DNA topoisomerase I (EC 5.99.1.2) have been obtained by immunochemical scree...

Nitiss(J),Wang(J C) Proc Natl Acad Sci U S A 1988-11-21

...TOP1 gene encoding DNA topoisomerase I is disrupted. This shows that DNA topoisomerase I is the sole target of camptothe...