Choder(M) Genes Dev 1992-01-21

...TOP1). Specifically, these two processes are much slower in top1 mutants, as their mRNA levels and transcriptional rate ...

Alsner(J),Svejstrup(J Q),Kjeldsen(E),Søren... J Biol Chem 1992-08-06

...top1 Saccharomyces cerevisiae strain. By immunostaining, the 70-amino acid domain is shown to be necessary for nuclear l...

Schultz(M C),Brill(S J),Ju(Q),Sternglanz(R... Genes Dev 1992-08-14

Previous work has shown that rRNA synthesis is strongly inhibited in yeast top1-top2 double mutants. Here, we show that ...

Zhou(B S),Beidler(D R),Cheng(Y C) Cancer Res 1992-08-28

...TOP1), a DNA unwinding enzyme, plays an essential role in several cellular functions; however, regulation of TOP1 activi...

Koo(H S),Lau(K),Wu(H Y),Liu(L F) Nucleic Acids Res 1992-11-25

...top1 strains of Saccharomyces cerevisiae. This positive supercoiling activity is dependent on the presence of bacterial ...

Bailis(A M),Arthur(L),Rothstein(R) Mol Cell Biol 1992-11-16

...TOP1 and TOP2, do not affect the rate of recombination between the SAM genes. The top3 mutation also changes the distrib...

Riou(J F),Helissey(P),Grondard(L),Giorgi-R... Mol Pharmacol 1991-12-19

...top1 gene under the control fo the GAL1 promoter, indicating that Topo I inhibition is responsible for the yeast cytotox...

Miyake(S),Tanaka(A),Yamamoto(M) Curr Genet 1991-12-16

...top1 on the right arm of chromosome II; that ypt2 is 2.5 cM apart from ura2 on the right arm of chromosome I; that ypt3 ...

Boreham(D R),Trivedi(A),Weinberger(P),Mitc... Radiat Res 1990-09-21

...top1) resulted in the constitutive expression of increased radiation resistance equivalent to that induced by a heat sho...

Aguilera(A),Klein(H L) Mol Cell Biol 1990-05-02

...TOP1 gene in an alpha-helical stretch of 129 amino acids near the carboxy-terminal region of both proteins. The ethyl me...