Gerhold(D),Thiyagarajan(M),Kmiec(E B) Nucleic Acids Res 1994-11-03

...top1 gene disruption mutant was constructed by replacing the genomic TOP1 gene, with a top1::HygR null allele. This muta...

Baumgärtner(B),Klett(C),Hameister(H),Richt... Mamm Genome 1994-03-28

...TOP1. The active mouse gene was mapped to the distal Chromosome (Chr) 2. In addition, the mouse genome contains one trun...

Di Mauro(E),Camilloni(G),Verdone(L),Casert... Mol Cell Biol 1993-11-18

...TOP1 gene, which codes for Saccharomyces cerevisiae DNA topoisomerase I, affects the rate of transcription starting at t...

Lee(M P),Brown(S D),Chen(A),Hsieh(T S) Proc Natl Acad Sci U S A 1993-08-30

...top1 to the X chromosome at 13C1 and isolation of top1 genomic DNA. Using P-element mutagenesis, we have isolated a muta...

Benedetti(P),Fiorani(P),Capuani(L),Wang(J ... Cancer Res 1993-10-01

...TOP1 complementary DNA in YCpGAL1-hTOP1, a plasmid constructed for the expression of the human enzyme in yeast. A yeast ...

Gartenberg(M R),Wang(J C) Proc Natl Acad Sci U S A 1993-12-29

...top1 top2ts strains of S. cerevisiae expressing Escherichia coli DNA topoisomerase I, accumulation of positive supercoil...

Knab(A M),Fertala(J),Bjornsti(M A) J Biol Chem 1993-12-01

...top1N726L or top1 vac was overexpressed but viable when htop1 vac was overexpressed. These results suggest differences b...

Levin(N A),Bjornsti(M A),Fink(G R) Genetics 1993-05-06

...top1-103 causes RAD9-dependent cell cycle arrest in G2. We show that the Top1-103 enzyme nicks DNA in vitro, suggesting ...

Christman(M F),Dietrich(F S),Levin(N A),Sa... Proc Natl Acad Sci U S A 1993-09-23

...top1 cultures and not in preparations from stationary-phase top1 cultures. rDNA from a top1 strain does enter the gel if...

Longtine(M S),Enomoto(S),Finstad(S L),Berm... Genetics 1993-03-23

...TOP1, TEL1 and TEL2 do not influence TRS plasmid segregation. Unlike transcriptional repression at telomeres, TRS plasmi...