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TP53 BRCA1 CRISPR single-cell cancer

Beidler(D R),Chang(J Y),Zhou(B S),Cheng(Y ... Cancer Res 1996-02-13

...TOP1 interactions. Therefore, CPT resistance in the 100 and 300 lines was characterized by factors independent of TOP1, ...

Knab(A M),Fertala(J),Bjornsti(M A) J Biol Chem 1995-04-18

...top1 vac mutants were resistant to all of the camptothecin derivatives cytotoxic to wild-type TOP1-expressing cells. Thi...

Zou(J),Scocca(J R),Krag(S S) Arch Biochem Biophys 1995-04-19

...top1 and ade1.

Murakami(S),Yanagida(M),Niwa(O) Mol Gen Genet 1995-04-26

...top1+ gene (type I DNA topoisomerase) suppressed the instability of the largest circular minichromosome, whereas partial...

Fujimori(A),Harker(W G),Kohlhagen(G),Hoki(... Cancer Res 1995-04-12

...top1 cDNA from CEM/C2 identified mutations corresponding to two amino acid substitutions, Met370Thr and Asn722Ser. Asn72...

Pommier(Y),Jenkins(J),Kohlhagen(G),Leteurt... Mutat Res 1995-11-06

...top1-linked oligonucleotide after loss of the +1 and +2 nucleotides. Top1 religation activity appeared efficient since o...

Kauh(E A),Bjornsti(M A) Proc Natl Acad Sci U S A 1995-08-10

...top1 delta yeast cells expressing plasmid-borne wild-type DNA topoisomerase I, six dominant suppressors of camptothecin ...

Ohtake(Y),Wickner(R B) Mol Cell Biol 1995-06-02

...top1], mak7 [rpl4A], mak8 [rpl3], mak11, and mak16) had decreased free 60S subunits. Mutants with another three mak muta...

Goldwasser(F),Bae(I),Valenti(M),Torres(K),... Cancer Res 1995-06-12

...Top1 mRNA, measured by Northern blotting analysis, and top1 protein levels, measured by Western blotting, varied by 2-fo...

Ezekiel(U R),Towler(E M),Wallis(J W),Zasse... Curr Genet 1995-06-22

...TOP1, TOP2, and TOP3 genes.

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