Pourquier(P),Ueng(L M),Kohlhagen(G),Mazumd... J Biol Chem 1997-04-18

...top1) activity were examined in oligonucleotides containing a unique top1 cleavage site. The presence of uracils and aba...

Balestrazzi(A),Toscano(I),Bernacchia(G),Lu... Gene 1997-02-13

...top1 transcript, which was constructed using an antisense specific oligonucleotide. The top1 nucleotide sequence encoded...

Bryk(M),Banerjee(M),Murphy(M),Knudsen(K E)... Genes Dev 1997-02-18

...TOP1, which increases psoralen accessibility in rDNA, or HTA1-HTB1, which reduces histone H2A-H2B levels and causes loca...

Hoki(Y),Fujimori(A),Pommier(Y) Cancer Chemother Pharmacol 1997-09-10

...top1) and are active in cancer patients against a variety of refractory solid tumors and leukemia.,The present study fur...

Pourquier(P),Pilon(A A),Kohlhagen(G),Mazum... J Biol Chem 1997-11-17

...top1) and oligonucleotides containing a unique top1 cleavage site to study top1-mediated cleavage and recombination in t...

Pondarré(C),Strumberg(D),Fujimori(A),Torre... Nucleic Acids Res 1997-12-02

...top1) poison which traps top1 cleavable complexes; e.g. top1-linked DNA single-strand breaks with 5'-hydroxyl and 3'-top...

Desai(S D),Liu(L F),Vazquez-Abad(D),D'Arpa(P) J Biol Chem 1997-10-23

...TOP1 trapped in the cleavable complex. We have analyzed TOP1 in mammalian cell lines treated with CPT. When CPT-treated ...

Valenti(M),Nieves-Neira(W),Kohlhagen(G),Ko... Mol Pharmacol 1997-08-08

...top1) cleavage complexes by binding to the +1 base of the scissile strand of a top1 cleavage site. We demonstrate that 7...

Garinther(W I),Schultz(M C) Mol Cell Biol 1997-07-24

...top1-top2). Expression of wild-type topoisomerase II in strain top1-top2 fully restored assembly-driven supercoiling, an...

Megonigal(M D),Fertala(J),Bjornsti(M A) J Biol Chem 1997-06-16

...top1T722A expression increased rDNA recombination. In checkpoint proficient cells, pGAL1-induced top1 expression coincid...