van Hille(B),Clerc(X),Creighton(A M),Hill(... Br J Cancer 1999-11-30

...TOP1 and RAD52 proteins are involved in the mode of action of bisdioxopiperazine ICRF compounds, which thus express a mo...

Duann(P),Sun(M),Lin(C T),Zhang(H),Liu(L F) Nucleic Acids Res 1999-09-03

...TOP1) poison which induces TOP1-mediated DNA damage. Within minutes, a large increase in the linking number (over 10 lin...

Takebayashi(Y),Pourquier(P),Yoshida(A),Koh... Proc Natl Acad Sci U S A 1999-07-19

...top1). Purified top1 was then tested and found to produce cleavage complexes in the presence of Et743, whereas topoisome...

Borovitskaya(A E),D'Arpa(P) Oncol Res 1999-01-04

...TOP1, EC 5.99.1.2) cause the reversible stabilization of the TOP1-DNA covalent complex (cleavable complex). The cleavabl...

Pourquier(P),Ueng(L M),Fertala(J),Wang(D),... J Biol Chem 1999-04-29

...top1) when these lesions are introduced in the vicinity of a top1 cleavage site (Pourquier, P., Ueng, L.-M., Kohlhagen, ...

Yanase(K),Sugimoto(Y),Andoh(T),Tsuruo(T) Int J Cancer 1999-03-31

...TOP1 cDNA (TM1) and a neomycin-resistance gene to examine the effect of mutant DNA topoisomerase I (topo I) expression o...

Park(H),Sternglanz(R) Yeast 1999-06-29

...TOP1 and HPR1. The implications of these interactions for TOF2 function are discussed.

Beretta(G L),Binaschi(M),Zagni(E),Capuani(... Cancer Res 1999-09-07

...Top1 to establish whether the fusion protein had altered site specificity. Under conditions of reduced binding of Top1 t...

Gallagher(D S),Schläpfer(J),Burzlaff(J D),... Chromosome Res 1999-07-21

...TOP1) previously assigned to human chromosomes 10 or 20 (HSA10 or HSA20). Four of the genes were found represented in th...

Li(R),Mignot(E),Faraco(J),Kadotani(H),Cant... Genomics 1999-07-06

...TOP1). The resulting positive clones were characterized and shown to be compatible with an eightfold redundant library.