Reid(Robert J D),González-Barrera(Sergio),... Genome Res 2011-06-24

...TOP1) into the haploid yeast gene-disruption library. Overexpression of Top1 identified only one sensitive mutation, rpa...

Ryan(Denise),Rafferty(Mairin),Hegarty(Shau... Pigment Cell Melanoma Res 2011-02-23

...TOP1 as being amplified in melanoma tissues. TOP1 amplification was detected in a high percentage (33%) of tumours and w...

Zhu(Yuan Xiao),Tiedemann(Rodger),Shi(Chang... Blood 2011-06-28

...TOP1, VAMP2, and YY1. The strongest hit CDK5 also featured prominently in pathway analysis of primary screen data. Cycli...

Chamayou(S),Bonaventura(G),Alecci(C),Tibul... Cryobiology 2011-06-20

...TOP1, H1F0H1), chromosomal structure maintenance (SMC, SCC3, RAD21, SMC1A, SMC1B, STAG3, REC8), mitochondrial energetic ...

Kusari(Souvik),Zühlke(Sebastian),Spiteller... J Nat Prod 2011-07-08

...Top1 gene and rDNA, remained intact over subculturing, revealing that instability of biosynthetic genes of 1 was not ref...

Heideker(Johanna),Prudden(John),Perry(J Je... PLoS Genet 2011-08-24

...Top1-DNA adducts (Top1cc). We further identify Rad60, a SUMO mimetic and STUbL-interacting protein, and the SUMO E3 liga...

Chen(Xia),Ma(Wen-Li),Liang(Shuang),Liao(Zh... Ai Zheng 2010-06-01

...TOP1, HOXA9, DEK, PABPC1 and IMPDH2, were differentially expressed during EBV reactivation. Many of them were oncogenic....

Hoskins(Janelle M),Rosner(Gary L),Ratain(M... Pharmacogenomics 2010-03-25

A recent study found that variation in camptothecin pharmacodynamic genes (TOP1, PARP1, TDP1 and XRCC1) correlated with ...

Cinelli(Maris A),Cordero(Brenda),Dexheimer... Bioorg Med Chem 2010-01-19

The aromathecin topoisomerase I (top1) inhibitors offer promising scaffolds for the development of novel cancer chemothe...

Kieber(J J),Tissier(A F),Signer(E R) Plant Physiol 2010-07-06

...TOP1 probe. The cDNA clones include a 2748-base pair open reading frame predicting an amino acid sequence that is highly...