Gongora(Céline),Vezzio-Vie(Nadia),Tuduri(S... Mol Cancer 2011-09-20

...TOP1) is a nuclear enzyme that catalyzes the relaxation of supercoiled DNA during DNA replication and transcription. TOP...

Kusari(Souvik),Zühlke(Sebastian),Spiteller... J Nat Prod 2011-07-08

...Top1 gene and rDNA, remained intact over subculturing, revealing that instability of biosynthetic genes of 1 was not ref...

Nishioka(Masanori),Shimada(Mitsuo),Kurita(... Cancer Genomics Proteomics 2011-07-22

...TOP1)), and cell proliferation (integrin, beta 1 (ITGB1))-related genes. In the immunohistochemistry of MMP7, 4 responde...

Palle(Komaraiah),Vaziri(Cyrus) Cell Cycle 2011-09-28

...Top1) covalent or cleavage complexes (Top1ccs) that block leading-strand DNA synthesis and elicit DNA Double Stranded Br...

Balestrazzi(Alma),Confalonieri(Massimo),Ma... J Plant Physiol 2011-06-23

The expression profiles of genes involved in DNA repair, namely MtTdp1 (tyrosyl-DNA phosphodiesterase), top1 (DNA topois...

Khurana(Bharat),Zhuang(Lei),Moitra(Prasun ... Virol J 2011-01-31

...TOP1 requires hu-TOP1 residues 236 and 237, the same residues required to enhance the infectivity of progeny virions whe...

Zhu(Yuan Xiao),Tiedemann(Rodger),Shi(Chang... Blood 2011-06-28

...TOP1, VAMP2, and YY1. The strongest hit CDK5 also featured prominently in pathway analysis of primary screen data. Cycli...

Chamayou(S),Bonaventura(G),Alecci(C),Tibul... Cryobiology 2011-06-20

...TOP1, H1F0H1), chromosomal structure maintenance (SMC, SCC3, RAD21, SMC1A, SMC1B, STAG3, REC8), mitochondrial energetic ...

Heideker(Johanna),Prudden(John),Perry(J Je... PLoS Genet 2011-08-24

...Top1-DNA adducts (Top1cc). We further identify Rad60, a SUMO mimetic and STUbL-interacting protein, and the SUMO E3 liga...

Kurtzberg(Leslie S),Roth(Stephanie),Krumbh... Clin Cancer Res 2011-09-15

...Top1) inhibitors, such as Genz-644282, topotecan, irinotecan/SN-38, and ARC-111, and examines their activity in several ...