Shimamoto(Yuji),Nukatsuka(Mamoru),Takechi(... Int J Mol Med 2016-10-27

...TOP1); oxaliplatin-related excision repair cross-complementing 1 (ERCC1); biologic agent-related vascular endothelial gr...

Tikhomirov(Alexander S),Shchekotikhin(Andr... J Med Chem 2016-05-04

...Top1/Top2-mediated DNA relaxation, reduced NAD(+)/NADH ratio through tNOX inhibition, suppression of a NAD(+)-dependent ...

Husain(Afzal),Begum(Nasim A),Taniguchi(Tak... Nat Commun 2016-06-15

...TOP1 knockdown. In contrast, FACT knockdown inhibits association of TOP1 with H3K4me3, and severely reduces DNA cleavage...

Azevedo(Cristina),Saiardi(Adolfo) Biochem Soc Trans 2016-10-31

...Top1 interaction and impairs Top1 enzymatic activity, namely relaxing supercoiled DNA. Modulation of cellular levels of ...

Peres(Mihaela),Xu(Helian),Wu(Gang) PLoS One 2016-07-19

...top1 destination networks and top1 origin networks in order to understand their skeletal construction and community dyna...

Bu(Huajie),Baraldo(Giorgia),Lepperdinger(G... Exp Gerontol 2016-11-01

...TOP1), an enzyme controlling DNA topology, was identified as a target of mir-24, whose expression was induced by oxidati...

Johnson(Michael E),Grassetti(Andrew V),Tar... Arthritis Res Ther 2016-10-06

...TOP1), and centromere proteins (CENP). IP eluates were then analyzed by LC-MS/MS to identify novel proteins and complexe...

Jandu(Haatisha),Aluzaite(Kristina),Fogh(Lo... BMC Cancer 2016-10-05

...Top1 inhibitor LMP400. The resistant cell lines were characterized by Top1 down-regulation, changed isoelectric points o...

Rechkunova(N I),Lebedeva(N A),Lavrik(O I) Bioorg Khim 2016-04-28

...Top1) to DNA, Tdp1 is able to initiate the cleavage of the internal AP sites in DNA and their following repair. Tdp1 was...

Al-Hatmi(Abdullah M S),Van Den Ende(A H G ... Fungal Biol 2016-10-13

...TOP1) and phosphoglycerate kinase (PGK), in combination with other routinely used markers such as TEF1, in an analysis o...