Hu(Y),Yang(L),Zhou(W),Chen(H),Li(Y),Song(B... J Cardiovasc Dev Dis 2026-02-27

...TOPORS, remains unclear. This study investigates how TOPORS regulates AD pathogenesis through SUMOylation. AD and normal...

Khan(AO) Retina 2026-08-21

...TOPORS and PRPF31. Regarding PCARE-related disease, 7/8 cases (3/4 families) harbored the same homozygous pathogenic var...

Huang(M),Qin(Y),Yang(Q),Chen(X),Chen(K) BMC Cancer 2026-02-27

...TOPORS, and SENP5—were selected using the LASSO-RSF framework to develop a refined prognostic model. This model demonstr...

Kim(A),Gopalakrishnan(P),Suárez-Pizarro(M)... NPJ Breast Cancer 2026-05-23

...TOPORS, a dual ubiquitin- and SUMO-ligase, among novel USP7 substrates. TOPORS interacts with the BRCA1-A DNA damage rep...

Abusheikha(AJ),Johnson(CSC),Snyder-Mackler... Front Nutr 2025-00-00

...TOPORS, ARPC2, and ENSMFAG00000050714 [LncRNA]) in subordinate relative to dominant monkeys. These alterations were asso...

Li(W),Wang(Y),Guo(W),Wen(D) Front Cell Dev Biol 2025-00-00

...Topors, thereby increasing the stability of p53 by reducing its ubiquitination. This ultimately influences the sensitivi...

Czub(Barbara),Shah(Amna Z),Alfano(Giovanna... PLoS One 2016-07-26

...TOPORS, a dual E3 ubiquitin and SUMO1 ligase, forms a component of the UPS and selected substrates for its enzymatic act...

Coussa(Razek Georges),Chakarova(Christina)... Invest Ophthalmol Vis Sci 2016-04-28

...TOPORS, two mutations (8%) in PRPF31, and one mutation (4%) in IMPDH1. Four mutations were novel. We identified new muta...

Luxton(Hayley J),Barnouin(Karin),Kelly(Gav... Mol Oncol 2014-12-17

...TOPORS, an E3 ligase that also regulates p53 modification may be responsible for LYRIC/AEG-1 ubiquitin modification. Ove...

Minchenko(D O),Danilovskyi(S V),Kryvdiuk(I... Fiziol Zh 2014-12-19

...TOPORS (topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase), TP53BPI (TP53 bindingprotein 1), TP...