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MRE11 suppresses germline mutagenesis at meiotic double-strand breaks in mice...

Lukaszewicz(A),Wilson(TE),Kim(S),Keeney(S)... bioRxiv 2026-02-15

SPO11 forms hundreds of double-strand breaks (DSBs) to initiate meiotic recombination that is normally error-free. Howev...

The Poly(rC) binding protein 2 is required for spermatogenesis by regulating ...

Xiong(Q),Qin(Z),Li(Y),Yim(WY),Wang(Z),Tan(... Int J Biol Macromol 2026-03-00

...Spo11, Tdrd5 and Brme1) and spermiogenesis (Eif4g3, Piwil1 and Dlec1), thereby orchestrating mRNA stability and alternat...

Meiosis-specific genes play roles in ploidy reduction in Cryptococcus neoform...

Bian(Z),Wilhoit(K),Liber(J),Peer(A),Xu(Z),... Proc Natl Acad Sci U S A 2026-06-02

...SPO11, are critical for stable inheritance of a diploid genome in the daughter cells. Specifically, deletion of these ge...

MRE11 suppresses germline mutagenesis at meiotic double-strand breaks in mice...

Lukaszewicz(A),Wilson(TE),Kim(S),Keeney(S)... Genes Dev 2026-08-26

SPO11 forms hundreds of double-strand breaks (DSBs) to initiate meiotic recombination that is normally error-free. Howev...

Repair and misrepair of telomeric DNA in dynamic interactions with PML nuclea...

Salmina(K),Rumnieks(F),Pjanova(D),Vainshel... Nucleus 2026-12-00

...SPO11 and DMC1. On the 3rd week, the cells de-polyploidised and returned to the normal cycle, telomerase, and mitosis. A...

FeM-ID: a biotin labeling-based approach for the dissection of female meiotic...

Feng(C),Wang(B),Cuacos(M),Lorenz(J),Hartma... Plant Cell 2026-02-16

...spo11-1), meiotic recombination 11 (mre11), and mutL homolog 3 (mlh3), facilitating cytological studies of heterochiasmy...

Adaptive Spo11 RNA editing gate optimizes meiosis I pace and mitotic prolifer...

Wu(M),Liu(J),Han(J),Huang(J),Feng(C),Jiang... Sci Adv 2026-06-12

Spo11-mediated DNA double-strand breaks (DSBs) are essential for meiotic recombination, yet how Spo11 activity is tempor...

Meiotic gene variants contribute to recurrent blastulation failure.

Chen(X),Leng(L),He(W),Li(W),Li(L),Zhang(X)... Hum Reprod Open None

...SPO11, MEI1, REC114, ANKRD31, DMC1, CNTD1, MLH3, SYCE1, and SYCP2), while three male patients carried MEIKIN variants. F...

Break-induced replication forms long mutable single-strand DNA during meiosis...

Twarowski(JM),Kramara(J),Seuferer(GJ),Renn... Nat Commun 2026-06-20

...Spo11-induced DSBs, and that break-induced replication and hyper-resection of DSBs are the primary mechanisms underlying...

Stage-Specific Transcriptomic Analysis Reveals Molecular Basis of Ovarian Ste...

Sun(X),Li(L),Cheng(L),Meng(Z),Xu(W),Liu(X) Animals (Basel) 2026-04-28

...spo11, dmc1, sycp3) were consistently upregulated in triploids across all stages, while the DNA repair gene rad51 was pa...

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