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NRZ complex facilitates virus infection via enhancing ER-LD contacts.

Li(Z),Xing(Y),Huang(X),Tian(B),Mei(J),Fu(X... J Cell Biol 2026-03-02

...RINT1) and zeste white 10 (ZW10), is essential for HCV-induced ER-LD association and viral infection. Mechanistically, R...

Transcriptional and Alternative Splicing Regulation of Autophagy and Vesicle ...

Zheng(Z),Chi(H),Liu(X),Chen(X),Pan(Y),Gong(H) Animals (Basel) 2026-04-20

...rint1 (RAD50 interactor 1). Weighted gene co-expression network analysis (WGCNA) of DEGs identified mapk9 (mitogen-activ...

BRIP1-mediated RINT1 acetylation and NF-κB activation promote DNA repair and ...

Wu(H),Zhang(J),Yu(Y),Wang(W),Huang(J),Lin(... Cancer Lett 2026-05-01

...RINT1 at lysine 728, thereby strengthening RINT1-RAD50 interaction, facilitating MRE11-RAD50-NBS1 complex assembly, and ...

Functional analysis of novel and recurrent RINT1 variants in patients with in...

Aoki(T),Inui(A),Ogata(Y),Igarashi(A),Yanag... J Hum Genet 2026-01-00

Rad50-interacting protein (RINT1) interacts with the endoplasmic reticulum (ER) tethering and SNARE complex, playing a c...

Cytokine-Induced Cytotoxicity and Extracellular Matrix Abnormalities in Hepat...

Zhang(Y),Ogata(Y),Nadanaka(S),Kitagawa(H),... FASEB J 2025-08-15

...RINT1) deficiency has been implicated in recurrent acute liver failure (RALF) triggered by fever or infections. RINT1, t...

Unraveling the role of coagulation-related genes in esophageal squamous cell ...

Deng(L),Fang(C),Zhang(W),Zhu(Z),Gu(Y),Gu(P... Front Oncol 2025-00-00

...RINT1, and SPTB-in ESCC. A prognostic model based on these genes effectively stratified patients and demonstrated robust...

Recurrent acute liver failure and neutropenia caused by a novel homozygous RI...

Nuzhnaya(Е),Marakhonov(A),Prokhorov(N),Kan... Hum Genomics 2025-10-07

...RINT1, NBAS have been implicated in RALF and are classified as infantile liver failure syndromes type 2 and 3 (ILFS2 and...

Recurrent fever-associated acute liver failure and cranial dysmorphism in chi...

Cui(Y),Abudu(F),Simijiang(Y) Front Pediatr 2025-00-00

Mutations in the RINT1 gene represent a rare genetic cause of recurrent fever-associated acute liver failure (ALF) accom...

Rint1 inactivation triggers genomic instability, ER stress and autophagy inhi...

Grigaravicius(P),Kaminska(E),Hübner(C A),M... Cell Death Differ 2016-11-01

...Rint1 in neuroprogenitors led to death at birth. Depletion of Rint1 caused genomic instability due to chromosome fusion ...

BluepRINT for moderate-to-low penetrance cancer susceptibility genes needed: ...

Ngeow(Joanne),Eng(Charis) Cancer Discov 2015-02-24

RINT1 is a novel moderately penetrant cancer susceptibility gene seen in breast cancer as well as possibly in Lynch synd...

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