Translesion synthesis is a major DNA damage bypass pathway in which specialized DNA polymerases, such as pol η and Rev1,...
...REV1 is central to coordination of G4 resolution, replication fidelity, and tolerance of G4 stabilization. REV1 loss swi...
...Rev1's single BRCT domain, is required for the inhibitory activity of Rev1 on undamaged DNA. Mutations in the M1 motif r...
...REV1-Pol ζ complex and the MCM8-MCM9-HROB DNA helicase complex; 2) Fanconi Anemia (FA) proteins and the mitotic DNA repa...
...REV1 and LIG1 increase germline mutation rates, and thus that rare mutator alleles segregate in population cohorts.
...Rev1 and SOD2, thereby impairing ROS scavenging and sensitizing tumor cells to RAI-induced oxidative stress. In vivo, th...
...Rev1, protects against both infections but induces antibodies detected by S-LPS-based tests used for B. melitensis surve...
...REV1+ haploids than in REV1+ diploids. Deleting the REV1 gene caused this difference to vanish, with mutation rates in h...
...Rev1 vaccine strain. Although its initial rate of infection was comparable to B. melitensis 16M, Rev1 exhibited a delay ...
...Rev1 axis was further supported by reduced formation of MAD2L2-Rev1 complexes, as assessed by proximity ligation assay. ...
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