...RAD51C [1]. The 23 patients with GPVs had 43 relatives eligible for cascade test and 22 non-eligible relatives (includin...
...RAD51C/PALB2 together, providing a plausible HR-inactivation mechanism for 71.4% of HRD tumors. Our modelled estimate of...
...RAD51C promoter methylation and HRD was assessed in 244 samples without a PV in HRR genes. BRCA1/RAD51C promoter methyla...
...RAD51C-XRCC3 (CX3) complex of RAD51 paralogs participates in the FA pathway of R-loop tolerance mechanism. CX3 complex s...
...RAD51C/D, BARD1) and genes associated with classic tumor predisposition syndromes (TP53, PTEN, STK11, CDH1, NF1) are ass...
...RAD51C) and proteins (e.g., RAB2B, GPN1, GSTM4) with putative mechanistic roles. Fine-mapping refined several signals (G...
...RAD51C, XRCC3, RAD51D and XRCC2. Here, using cryo-electron microscopy, we find that the RAD51-XRCC3-RAD51C complex (RAD5...
...RAD51C promoter methylation assays, shallow whole genome and multiplex immunofluorescence. Homologous recombination defi...
...RAD51C-RAD51D-XRCC2 (BCDX2) and RAD51C-XRCC3 (CX3), that act independently at different stages of homologous recombinati...
...RAD51C, RAD51D, and TP53) to chemotherapy-induced gonadotoxicity remains unclear. Although animal data shows depletion o...
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