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RAD51AP1-MYC-Sam68 positive transcriptional feedback loop maintains lung cancer…

Liu(R),Li(M),Hu(Z),Yang(S),Zhu(G),Cao(P),Fan… iScience 2026-09-18

...RAD51AP1-MYC-Sam68-RAD51AP1 positive transcriptional feedback loop. Targeting this cascade has the potential to reverse ...

G quadruplex DNA facilitates a pervasive path to homologous recombination.

Thakur(BL),Basak(P),Khurana(S),Sharma(S),Lai… bioRxiv 2026-06-07

...RAD51AP1, WDR48, and USP1, and requires G4 motifs within the homologous repair template. DHX36 loss partially restores H...

PARG Governs a PARylation-Ubiquitination Toggle that Stabilizes RAD51AP1 to Dri…

He(H),Hu(Y),Lu(Y),Deng(M),Bao(Q),Zu(D),Zhong… Cancer Res 2026-06-18

...RAD51AP1, thereby protecting RAD51AP1 from proteasomal degradation. Consequently, loss of PARG destabilized RAD51AP1 and...

Glutamine Deprivation Triggers Tribbles Homolog 3 Dependent G-Quadruplex Resolu…

Ji(Q),Sun(X),Sun(Z),Li(M),Cheng(X),Tian(S),T… Adv Sci (Weinh) 2026-05-00

...RAD51AP1 promoter regions that would otherwise suppress transcription. In vivo, TRIB3 silencing suppresses HCC xenograft...

TRF2-RAP1 inhibits homology-directed repair of telomeres by promoting BLM-media…

Liang(F),Chang(S) Nucleic Acids Res 2026-03-19

...RAD51AP1-dependent manner. In classic DNA double-strand break repair, RAD51AP1 promotes R-loop formation and enables RAD...

DLGAP5 protects glioblastoma cells against DNA damage through E2F1-transcripted…

Liu(Y),Chen(R),Liu(G),Chen(J),Zhou(J),Chen(Y… Biochim Biophys Acta Mol Basi… 2026-08-00

...RAD51AP1, and importantly, the enforced expression of E2F1 recovers RAD51AP1 expression that largely rescues DNA damage ...

[Screening of mRNA molecules targeted by RAD51AP1 protein in human lung adenoca…

Liu(CX),Li(SQ),Dong(H),Wang(HF),Wang(LX) Zhonghua Yu Fang Yi Xue Za Zhi 2026-08-06

...RAD51AP1-shRNA and RAD51AP1-Over groups(0.96±0.10 vs. 0.92±0.07, t=0.62;vs. 0.94±0.03, t=0.38;P>0.05). RAD51AP1 mRNA exp...

Functional phosphoproteomic analysis of SMG1 in nonsense-mediated mRNA decay an…

Pai(AKA),Dcunha(L),Gopalakrishnan(AP),Ummar(… Front Syst Biol None

...RAD51AP1, NBN, PNKP, TP53BP1, and PBRM1. UALCAN analysis further revealed differential regulation of SMG1 phosphosites a...

ITGA5 promotes homologous recombination mediated radioresistance in esophageal …

Huang(X),Liu(J),Ren(J),Yuan(J),Huo(W),Zhang(… Oncogene 2026-09-04

...RAD51AP1. This signaling axis enhances homologous recombination repair efficiency by facilitating RAD51 chromatin loadin...

Epigenetically elevated RAD51AP1 regulates the RAD51-UAF1 complex contributing …

Chang(Y),Yang(J),Li(Z),Zhu(X),Jiang(T),Wang(… Chin Med J (Engl) 2026-05-20

...RAD51AP1 gene in TMZ resistance in EGFRvIII -bearing glioblastoma. The CRISPR/Cas9 library identified RAD51AP1 , a synth...

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