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Wu(H),Zhang(J),Yu(Y),Wang(W),Huang(J),Lin(... Cancer Lett 2026-05-01

...RAD50 interaction, facilitating MRE11-RAD50-NBS1 complex assembly, and augmenting HR-mediated DNA repair. Enhanced repai...

Aird(EJ),Serrano-Benitez(A),Siegner(SM),Ca... Nat Commun 2026-02-25

...RAD50-NBS1 (MRN)-mediated resection by binding and melting staggered DNA ends, thereby promoting accurate end joining. O...

Li(X),Xiang(Y),Gao(J),Zong(H),Li(M),Gao(R)... J Ovarian Res 2026-02-06

...RAD50. Additionally, LINC00467 ASO played a synergistic role with olaparib in HGSOC PDX models. CONCLUSION: Our results ...

Sun(H),Yang(B),Wang(F),Xie(R),Chen(T),Chen... Gene 2026-04-15

...RAD50, which is a key component of the MRE11-RAD50-NBS1 (MRN) complex involved in DNA double-strand break repair. Merely...

Lang(GT),Weng(XL),Liu(Y),Hu(X),Shao(ZM),Hu(Z) Pathophysiology 2026-01-20

...RAD50, DMD, ARSA, and ABCC6 demonstrating recurrent mutations in MaBC. As the inaugural germline genomic investigation o...

Li(H),Song(Y),Cong(Y),Wang(C),Chen(K),Liu(... Oncogene 2026-03-00

...RAD50. Mechanistically, YEATS2 increases chromatin accessibility at the RAD50 promoter region by recognizing H3K27ac and...

Ma(T),Wu(J),Li(S),Chen(J) Cancer Res 2026-07-22

...RAD50-NBS1 (MRN) complex, rather than MUS81 or ERCC1/XPF, was the principal mediator of cruciform DNA processing followi...

Gopinathan(A),Jain(V),Sharma(D),Kumar(PRV) Sci Rep 2026-03-16

...RAD50, suggesting that HPRT mutation may influence DNA damage response pathways. Our findings indicate that chronic expo...

Su(Z),Shen(H),Sun(J),Kong(X),Sun(W) J Am Heart Assoc 2026-08-04

...RAD50-NBS1 (MRN) perturbation. Single-cell analyses identify CRABP2 as a fibroblast-enriched gene upregulated in profibr...

Dell'Elice(A),Palmarini(C),Anaclerio(F),Pi... J Med Genet 2026-07-24

...RAD50, BLM, WRN, PMS1 and FANCA. These variants may represent candidate susceptibility loci requiring further clinical a...