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Incremental Prognostic Value of Pericardial Adipose Tissue Radiomic Phenotype...

Zhang(TY),Liu(Y),Chen(SZ),Wu(LM),Pu(J),Xu(... J Magn Reson Imaging 2026-07-00

...rad1 was a significant independent factor associated with MACE after adjusting for both clinical (HR: 0.937) and MRI (HR...

Mechanistic diversity of clamp loading at small DNA gaps.

Zheng(F),O'Donnell(ME),Li(H) J Biol Chem 2026-08-10

DNA sliding clamps, including PCNA (proliferating cell nuclear antigen) and the 9-1-1 (RAD9-RAD1-HUS1 in humans) complex...

Class II HDAC Clr3-mediated H2B deacetylation promotes DNA damage and replica...

Liu(L),Zhu(R),Yin(J),Zhang(F),Lu(G),Fang(L... FEBS Lett 2026-07-11

...Rad1-Hus1. H2B hyperacetylation and Clr3 loss disrupted chromatin compaction, impaired sister chromatid cohesion, suppre...

Energetically equivalent structural transitions in the Rad17-Rad9-Hus1-Rad1-R...

Fukumoto(Y),Yuki(R),Ogra(Y) Nucleic Acids Res 2026-02-05

...Rad17, Rad9-Hus1-Rad1 (9-1-1), and Rhino during ATR-DDR progression. Biochemical and computational analyses revealed the...

The telomere-binding protein KU is required for DSB repair in rice mitosis bu...

Zhao(Y),Wang(B),Pang(Y),You(H),Cao(L),Zhon... New Phytol 2026-07-00

...rad1) nor genetically interacted with key HR factors (ZIP4 and MER3). Taken together, our findings establish rice meiosi...

Construction of a novel signature based on CRISPR-Cas9 screening for prognost...

Xiao(WT),He(JY),Yang(D),Xun(Y) BMC Cancer 2026-05-14

...RAD1, RBBP8, TUBA1B, and VPS28) was developed. This signature effectively stratified patients into high- and low-risk gr...

CTPS1 is an unexplored vulnerability in breast and ovarian cancer.

Wang(X),Emch(MJ),Voll(LA),Epp(R),Rodman(EP... Theranostics None

...RAD1, RAD9A, and RHOA) were identified as potential TNBC selective dependencies. Among these, CTPS1 was prioritized for ...

A point mutation in the FAT domain constitutively increases the kinase activi...

Dev(K),Rider(SD),Singh(B),Saini(A),Xu(YJ) PLoS Genet 2026-06-00

...Rad1-Hus1 (9-1-1) complex specifically in the DNA replication checkpoint, not the damage checkpoint pathway. Since the m...

YOLO26x-based automated fracture detection on radiographs and its impact on r...

Pamuk(GG),Yüce(M),Öztürk(S),İşleyen(ME),Ka... Eur J Radiol 2026-10-00

...RAD1: 76.2 % → 83.4 %, p = 0.001; RAD3: 75.6 % → 83.4 %, p < 0.001; Holm-corrected), with sensitivity gains of 2.4-16.4 ...

Distinct ATRX functions cooperate with 9-1-1 and CST complexes to safeguard r...

Segura-Bayona(S),Maric(M),Takaki(T),Manova... Nat Struct Mol Biol 2026-07-00

...RAD1 (9-1-1) clamp in ATRX-deficient cells. ATRX-CST synthetic lethality manifests following accumulation of telomeric G...

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