...PMS1 c.1258delC, MLH1 c.1291_1292delAT, NBN c.877delA, and EPCAM c.184 + 1G > A. The observed prevalence of clinically a...
...PMS1) and MutSα (MSH2-MSH6). We uncover the physical interaction between MBD4 and MutLβ and demonstrate that MBD4-mediat...
...PMS1 interactions. Overall, we established a validated, transferable assay for quantifying DNA R/H proteins in perturbat...
...PMS1 as the binding partner of MLH1 in dogs, rather than PMS2. A novel monoclonal antibody was developed to detect PMS1 ...
...PMS1 as therapeutic targets for slowing somatic expansion and outline key safety considerations for emerging MMR-modulat...
...PMS1 and PMS2). We revealed that PMS1 exhibits high epithelial-mesenchymal transition (EMT) characteristics and is assoc...
...Pms1 or Mlh1-Mlh2 exhibiting the strongest effects. Mutations in PMS1 and MLH3 were synergistic. We propose a model in w...
...PMS1). Analysis of the striatum identified 289 differentially expressed genes. The most significantly upregulated genes ...
...PMS1 heterodimer) is a poorly understood eukaryotic MutL complex. Recent genetic studies have implicated MutLβ in the pr...
...PMS1, to survive RFA-induced stress. This hypermutant phenotype grants a certain degree of growth recovery on Low Galact...
山东省济南市章丘区文博路2号
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