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Integrated Multi-Omics and Spatial Transcriptomics Identify FBLL1 as a Malign...

Xie(J),Guo(S),Xiao(Y),Zhang(Y),Hong(A),Che... Cells 2026-01-27

...Myc and multiple EGFR ligands, as well as decreased expression of hepatocyte functional markers. Consistently, modulatio...

SATB2 Induces Malignant Transformation and Cancer Stem Cell Characteristics, ...

Brown(C),Srivastava(S),Srivastava(R),Sriva... Cells 2026-02-02

...Myc, NANOG, and SOX2, consistent with a role in transcriptional regulation of genes linked to transformation, pluripoten...

Evaluation of the Osteogenic Potential of a NOTCH1 Agonist and Poloxamer 407 ...

Mohan(S),Kesavan(C) Biology (Basel) 2026-01-24

...myc, Cox2, and Hes1) in osteoblasts. A low dose of P407 in combination with 10 µM Yhhu3792 stimulated a significant incr...

Synthesis of potent human DHRS11 inhibitors and their efficacy against androg...

Miyamoto(Y),Hirai(W),Saka(T),Tanio(M),Kudo... Eur J Med Chem 2026-04-05

...Myc expression, and inhibited proliferation of MDA-MB-453 cells. Additionally, WH23 inhibited PI3K/AKT signaling, reduci...

c-Myc: Central regulator of autophagy and senescence in cancer.

Ji(S),Sun(T),Zhang(Q),Wu(M),Cao(Y),Gao(R),... Cancer Lett 2026-05-01

...Myc, autophagy, and senescence contribute to tumor biology. We then highlight the molecular mechanisms through which c-M...

Notch regulates mitochondrial activity in pupal diapause of Helicoverpa armig...

Song(Z),Liu(X),Yang(J) J Insect Physiol 2026-03-00

...Myc and TFAM. Consistent with previous findings that diapausing brains have lower mitochondrial activity, we propose tha...

Synthetic lethality of MCL-1 inhibition and CAR-T therapy in aggressive B-cel...

Gao(J),Zhao(X),Yin(Q),Hu(A),Qiu(K),Blackbu... Leukemia 2026-03-00

Aggressive B-cell lymphomas, driven by MYC overexpression, exhibit rapid progression, resistance to therapies, and poor ...

THY1+ cancer stem cells drive metastasis through a pseudohypoxic state shaped...

Wan(WH),Li(PL),Cao(WJ),Li(ZX),Xin(YQ),Wang... Nat Cell Biol 2026-03-00

...MYC signalling. Upon encountering neutrophils, THY1⁺ CSCs activate the THY1-Mac1 axis, triggering the Src-Akt/Erk pathwa...

Malva sylvestris Flower Extract Exhibits Antineoplastic Potential Against Hum...

Villani(V),Gismondi(A) Nutrients 2026-02-02

...MYC/AKT axis, justifying its antiproliferative property. In parallel, the transfection of tumour cells with pure synthet...

The Anti-Metastatic Role of Aspirin in Cancer: A Systematic Review.

Kanwal(R),Jawed(B),Zakir(SK),Gaudio(F),Mar... Int J Mol Sci 2026-01-28

...MYC signaling, regulation of redox-responsive pathways and impairment of anoikis resistance. This review provides the fi...

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