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Integrating Structural, Biochemical, and Cellular Perspectives on the TFIIH H...

Bravo(M),Fan(L) Biomolecules 2026-03-13

...ERCC2) helicases are integral components of the transcription factor IIH (TFIIH) complex, coordinating DNA unwinding dur...

[Cockayne syndrome: peculiarities of clinical manifestations and algorithm of...

Kungurtseva(AL),Popovich(AV),Tikhonovich(Y... Probl Endokrinol (Mosk) 2026-03-07

...ERCC2) and XPG (ERCC5)) and characterized by abnormal photosensitivity, congenital cataract, microcephaly, sensorineural...

m5C: Novel Diagnostic and Drug Repurposing Targets for Nonalcoholic Steatohep...

Chen(S),Duan(R),Qiu(J),Lei(Z),Chen(W),Li(X... Int J Genomics None

...ERCC2 and FOXC2 can be considered two upregulated m5C-associated hub genes involved in NASH pathogenesis, which were mai...

Identification of an ERCC2 mutation associated mutational signature of nucleo...

Stojkova(O),Börcsök(J),Sztupinszki(Z),Dios... bioRxiv 2026-02-19

...ERCC2 mutations in bladder cancer. Using publicly available panel sequencing data, we find that ERCC2 wild type (WT) bla...

19q13 amplification with AKT2 and ERCC2 gains in sarcomatoid carcinoma of the...

Morris(G),Vlachostergios(PJ),Rai(MP),Scher... Cancer Genet 2026-06-00

...ERCC2. Nine months postoperatively, the patient developed metastatic recurrence. This case contributes to the molecular ...

Systems Biology and Multi-Omics Determinants of Response to Bladder-Preservin...

Schițcu(VH),Munteanu(VC),Borz(MB),Cojocaru... Life (Basel) 2026-05-16

...ERCC2 and related pathways as determinants of chemo-radiation sensitivity. We then review reproducible transcriptomic su...

Genomic landscape of ERCC alterations in breast and gynecological cancers: im...

Canbek(S),Karaağaç(M),Ermiş(A),Türkan(Ş),T... Mol Biol Rep 2026-08-21

...ERCC2 (43.8%) and ERCC4 (25%), primarily presenting as missense variants (68.8%). Notably, 87.5% of the identified alter...

Comprehensive genomic profiling of synchronous invasive adenocarcinoma and sq...

Kang(DH),Hong(G),Kim(Y),Lee(JE),Lee(D),Yeo... Transl Lung Cancer Res 2026-01-31

...ERCC2 variant of uncertain significance in the squamous carcinoma, implicating functional compromise of mismatch repair ...

Investigating Genetic Risk to Oxaliplatin-Induced Sinusoidal Obstruction Synd...

Zhang(M),Wang(P),Kong(Y),Gaudio(DD),Parent... Mod Pathol 2026-05-00

...ERCC2, ABCB1, GSTP1, DPYD, MTHFR, ABCC2, UGT1A1, GSTT1, and GSTM1 known to be associated with oxaliplatin toxicity, as i...

Comparative genomic landscape of primary and metastatic bladder urothelial ca...

Ohtsu(A),Otani(Y),Arai(S),Rogachevskaya(A)... Int J Clin Oncol 2026-05-00

...ERCC2 were more frequently altered in primary tumors, whereas no individual genes were enriched in metastases; these dif...

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