...EML4-ALK) fusion variants have been identified, with variants 1-3 (V1-3) accounting for approximately 90% of cases. Howe...
...EML4-ALK variant 1 (V1) and variant 3 (V3) showed that V3 was associated with shorter progression-free survival (PFS) in...
...EML4-ALK fusion, a CDKN2A mutation (p.F90Lfs*30), and 11q13.3 (CCND1, FGF3, FGF4, and FGF19), CDK4, and MDM2 amplificati...
...EML4-ALK rearrangements. The median duration of neoadjuvant therapy was 5 months. The most common treatment-related adve...
...EML4 , were only seen in Spitz melanoma (SM) cases. TERT promoter mutations and c-MYC amplification were only seen in SM...
...EML4-ALK fusion, in which targeted therapy demonstrated efficacy. This advanced, unresectable epithelioid angiosarcoma c...
...EML4-ALK RNA) circulating biomarkers. We successfully validated THANOS's excellent biosensing performance in contrived p...
...EML4::NTRK3. Functional assays suggested their oncogenic potential and demonstrated responsiveness to the TK inhibitors ...
...EML4-ALK lung cancer cell lines were engineered to overexpress PD-L1, and effects on ALK TKI response were evaluated in ...
...EML4-ALK fusions (n = 2), KIF5B-RET fusion (n = 1), and KRAS p.G12C (n = 1). Targeted-containing regimens achieved rwORR...
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