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Dss1 facilitates Rad51 recruitment downstream of BRCA2/Brh2 in response to DN...

Juhl(L),Busch(L),Bagge(J),Xu(R),Kojic(M),M... DNA Repair (Amst) 2026-02-00

...Rad51. BRCA2 and Brh2, the BRCA2 orthologue in Ustilago maydis, enable recombinational repair of DNA by controlling Rad5...

An Inducible BRCA1 Expression System with In Vivo Applicability Uncovers Acti...

Irving(E),Morcavallo(A),Vohhodina-Tretjako... Cancers (Basel) 2026-01-20

...RAD51 foci formation and interaction with repair partners such as PALB2. In vivo, tumours expressing Δexon11 BRCA1 exhib...

Thyroid Hormone T3 Induces DNA Damage Response in Breast Cancer Cells.

Movshovitz(S),Sinberger(LA),Trabelsi(K),Ba... Int J Mol Sci 2026-01-09

...RAD51 and enrichment of DNA repair pathways following 24 h T3 exposure. Consistently, T3 increased γH2AX and 53BP1 nucle...

Recent advances in small molecule ATR kinase inhibitors as anticancer agents.

Singh(G),Sharma(R),Gautam(V),Dhingra(AK),H... Future Med Chem 2026-03-00

...RAD51 foci tests, and liquid biopsy DNA damage markers; develop advanced modalities including brain-penetrant scaffolds,...

The human RAD52 complex undergoes phase separation and facilitates bundling a...

Alshareedah(I),Pangeni(S),Dewan(PA),Honda(... Nucleic Acids Res 2026-01-22

...RAD51 fibrils comprise bundles of individual RAD51 nucleoprotein filaments. Additionally, we show that RAD52 induces end...

Magnolol suppresses TKI-resistant EGFR-mutant lung cancer by inhibiting EGFR ...

Chen(CC),Wang(TH),Leu(YL),Chan(CW),Chen(YX... Eur J Pharmacol 2026-02-28

...Rad51, leading to accumulation of DNA damage. These effects were enhanced when combined with brigatinib, a clinically ap...

Epigenetically elevated RAD51AP1 regulates the RAD51-UAF1 complex contributin...

Chang(Y),Yang(J),Li(Z),Zhu(X),Jiang(T),Wan... Chin Med J (Engl) 2026-05-20

...RAD51AP1 transcription in EGFRvIII cells. High expression levels of RAD51AP1 , promoted formation of the RAD51-UAF1 comp...

Circadian disruption increases sperm DNA damage through impaired CREB1-mediat...

Zhu(W),Hu(M),Zhang(Y),Lian(Y),Xu(Z),Huang(... Biol Reprod 2026-01-11

...RAD51. Luciferase reporter and ChIP assay confirmed the transcriptional regulation of CREB1 on BRCA1 expression. Overall...

The Molecular and Functional Landscape of Resistance to FOLFIRI Chemotherapy ...

Avolio(M),Leto(SM),Sassi(F),Lupo(B),Grassi... Cancer Discov 2026-02-06

...RAD51 recombinase. In tumoroids, forced RAD51 overexpression attenuated HR deficiency-related scars and chemotherapy-ind...

Cryo-electron microscopic visualization of RAD51 filament assembly and end-ca...

Greenhough(LA),Galanti(L),Liang(CC),Boulto... Science 2026-02-26

...RAD51B-RAD51C-RAD51D-XRCC2 (RAD51B complex) and XRCC3-RAD51C-RAD51D-XRCC2 (XRCC3 complex). The RAD51B complex promotes d...

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