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Dickreuter(E),Eke(I),Krause(M),Borgmann(K)... Oncogene 2016-08-15

...Rad50 and Nbs1. Further, we identified Ku70, Ku80 and DNA-PKcs but not poly(ADP-ribose) polymerase (PARP)-1 to reside in...

Aloraifi(Fatima),McDevitt(Trudi),Martinian... FEBS J 2016-02-25

...RAD50 (~ 3%), CHEK2 (~ 2%), TP53 (~ 1%), PALB2 (~ 1%), and MRE11A (~ 1%). However, we also identified novel pathogenic v...

Ross(Cody T),Roodgar(Morteza),Smith(David ... PLoS One 2016-01-18

...RAD50, and TM9SF2 were identified as possible candidates, among others. We failed to find many laboratory experiments co...

Park(Caroline),Suh(Yousin),Cuervo(Ana Mari... Nat Commun 2016-04-05

...Rad50-Nbs1) complex, which participates in early steps of particular DNA repair pathways. We propose that CMA contribute...

Huang(Qihong),Liu(Linlin),Liu(Junfeng),Ni(... BMC Mol Biol 2016-01-07

...Rad50.,We revealed that each of the four genes in the same operon, mre11, rad50, herA, and nurA, are essential for cell ...

Sheikh(Asfandyar),Hussain(Syed Ather),Ghor... Asian Pac J Cancer Prev 2016-01-08

...RAD50, BRIP1 and PALB2, which are frequently mutated in the general population. In this review, we discuss the entire sp...

Kinoshita(Eri),van Rossum-Fikkert(Sari),Sa... Biochimie 2016-02-04

...RAD50 binds DNA although not as oligomers. RAD50 alone was not functional in tethering DNA molecules. ATP increased form...

Gurung(Resham Lal),Lim(Shi Ni),Low(Grace K... J Nutrigenet Nutrigenomics 2016-04-22

...RAD50. Co-treatment with MST-312 and the poly(ADP-ribose) polymerase 1 (PARP-1) inhibitor PJ-34 further enhanced growth ...

Kim(Young-Jung),Kim(Tae-Won),Park(So-Ra),K... Environ Toxicol Pharmacol 2016-06-07

...Rad50, and Nbs1 (MRN) complex is associated with DNA repair mechanisms in cisplatin-induced acute renal failure. Rats we...

Seifert(Florian Ulrich),Lammens(Katja),Hop... Acta Crystallogr F Struct B... 2016-03-07

Together with the Rad50 ATPase, the Mre11 nuclease forms an evolutionarily conserved protein complex that plays a centra...