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Ammous-Boukhris(N),Abdelmaksoud-Dammak(R),... BMC Cancer 2025-10-09

...RAD50, and BRIP1. Interestingly, four recurrent BRCA1 PVs were observed, one of them is novel. Germline BRCA1/2 PVs were...

Chen(Y),Chen(Z),Wang(H),Cui(Z),Li(KL),Song... Science 2025-10-09

...RAD50 to facilitate RAD50 recruitment to damage sites, thereby potentiating homologous recombination repair. Moreover, t...

Gatei(Magtouf),Kijas(Amanda W),Biard(Denis... Hum Mol Genet 2016-03-22

The MRE11/RAD50/NBN (MRN) complex plays a key role in detecting DNA double-strand breaks, recruiting and activating atax...

Al-Ahmadie(Hikmat),Iyer(Gopa),Hohl(Marcel)... Cancer Discov 2016-06-02

...RAD50 that attenuated ATM signaling which in the context of CHK1 inhibition contributed, via synthetic lethality, to ext...

Simoneau(Antoine),Robellet(Xavier),Ladouce... Cell Cycle 2016-05-09

...Rad50-Xrs2 (MRX) complex, is regulated by cell cycle-dependent phosphorylation specifically in mitosis. This modificatio...

Paingankar(Mandar S),Arankalle(Vidya A) Virus Res 2016-05-25

...RAD50 and TLE-4 interacted with HEV 5'UTR. RNA immuno-precipitation studies further confirmed the interaction of DHX9, D...

Aloraifi(Fatima),McDevitt(Trudi),Martinian... FEBS J 2016-02-25

...RAD50 (~ 3%), CHEK2 (~ 2%), TP53 (~ 1%), PALB2 (~ 1%), and MRE11A (~ 1%). However, we also identified novel pathogenic v...

Petroni(M),Sardina(F),Heil(C),Sahún-Roncer... Cell Death Differ 2016-10-14

...RAD50/NBS1 (MRN) complex is a major sensor of DNA double strand breaks, whose role in controlling faithful DNA replicati...

Dickreuter(E),Eke(I),Krause(M),Borgmann(K)... Oncogene 2016-08-15

...Rad50 and Nbs1. Further, we identified Ku70, Ku80 and DNA-PKcs but not poly(ADP-ribose) polymerase (PARP)-1 to reside in...

Kim(Young-Jung),Kim(Tae-Won),Park(So-Ra),K... Environ Toxicol Pharmacol 2016-06-07

...Rad50, and Nbs1 (MRN) complex is associated with DNA repair mechanisms in cisplatin-induced acute renal failure. Rats we...