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Pancreatic cancer organoids derived from EUS-guided fine needle aspiration sp...

Oyama(S),Matsuda(A),Murakami(R),Kakizaki(Y... Sci Rep 2025-07-03

...RAD50 have been identified as genes associated with gemcitabine resistance. Additionally, SLC25A10 and MAP3K9 were ident...

WDR11-DT enhances radiosensitivity via promoting PARP1 degradation and homolo...

Yang(Y),Li(Z),Yu(X),Zheng(Y),Yu(Y),Yang(M)... Cancer Lett 2025-08-10

...RAD50, and suppresses radiotherapy-triggered HR repair. WDR11-DT-induced dual restraints of PARP1 and the HR pathway lea...

Cytokine-Induced Cytotoxicity and Extracellular Matrix Abnormalities in Hepat...

Zhang(Y),Ogata(Y),Nadanaka(S),Kitagawa(H),... FASEB J 2025-08-15

RAD50-interacting protein1 (RINT1) deficiency has been implicated in recurrent acute liver failure (RALF) triggered by f...

Structural basis for DNA break sensing by human MRE11-RAD50-NBS1 and its regu...

Fan(Y),Kuybu(F),Cui(H),Lammens(K),Chen(JX)... Nat Commun 2025-09-18

The MRE11-RAD50-NBS1 (MRN) complex is a central, multifunctional factor in the detection, signaling and nucleolytic proc...

Replication and Functional Prediction of Two GWAS-Reported SNPs Located on RA...

Ghani(MU),Sabar(MF),Bano(I),Ain(QU),Shahid... Res Sq 2025-09-17

...RAD50 gene are significantly associated with childhood-onset asthma. However, the biological role of RAD50, and its geno...

Defying the Prognostic Odds: A Case Report of Unexpected Complete Remission o...

Olliverrie(A),Konlack Mekontso(JG),Ren(J),... Case Rep Oncol Med 2025-00-00

...RAD50 genes, coding for enzymes involved in various deoxyribonucleic acid (DNA) repair pathways. These findings raise qu...

Flavonoids and nitrogen-containing heterocyclic phytochemicals regulate DNA r...

Singh(J),Khanduja(KL),Avti(PK) Biochem Biophys Res Commun 2025-09-08

...RAD50, NBN)] and miR-2909 expression analysis revealed greater regulation with N-compounds as compared to F-compounds in...

Survival Machine Learning Methods Improve Prediction of Histologic Transforma...

Kim(TY),Kim(TJ),Han(EJ),Min(GJ),Cho(SG),Ki... Cancers (Basel) 2025-09-09

...RAD50. This study highlights the clinical value of survival-based machine-learning methods integrated with NGS data to p...

LncRNA AC021683.2 promotes chemotherapy resistance in acute myeloid leukemia.

Li(L),An(XN),Ruan(YT),Liang(X),Hao(JL),Gao... iScience 2025-09-19

...RAD50, which mediated their roles in Ara-C-resistant AML cells. These findings demonstrated that the lncRNA AC021683.2 e...

IFI16 Enhances Chemosensitivity of Breast Cancer Cells by Inhibiting DNA Dama...

Ka(NL),Lim(GY),Kim(SS),Lee(MO) Biomol Ther (Seoul) 2025-11-01

...RAD50-NBS1 complex and disrupted the interaction between NBS1 and ataxia telangiectasia mutated (ATM), a critical step f...

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