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A systematic review and meta-analysis of somatic and germline DNA sequence bi...

Findlay(J M),Middleton(M R),Tomlinson(I) Ann Oncol 2016-02-09

...ERCC2 rs1799793, TP53 rs1042522, MDM2 rs2279744, TYMS rs34743033, ABCB1 rs1045642 and MTHFR rs1801133. Twelve germline m...

Testing the metal of ERCC2 in predicting the response to platinum-based therapy.

Turchi(John J),Woods(Derek S),VanderVere-C... Cancer Discov 2016-05-16

...ERCC2 that correlate with the response to platinum-based therapy. This work provides evidence that defects in NER can be...

Polymorphism of CYP3A4 and ABCB1 genes increase the risk of neuropathy in bre...

Kus(Tulay),Aktas(Gokmen),Kalender(Mehmet E... Onco Targets Ther 2016-08-30

...ERCC2, FGFR4, TP53, ERBB2, and CYP2C8 genes. Taxane-induced neurotoxicity during the treatment was evaluated according t...

Genetic variability in DNA repair proteins in age-related macular degeneratio...

Blasiak(Janusz),Synowiec(Ewelina),Salminen... Int J Mol Sci 2015-04-21

...ERCC2), XRCC1 and ERCC6 (CSB) have also been reported to be associated with AMD. These data confirm the importance of th...

Association between DNA repair gene polymorphisms and risk of glioma: a syste...

Adel Fahmideh(Maral),Schwartzbaum(Judith),... Neuro Oncol 2015-01-28

...ERCC2 (XPD), and XRCC1 may increase the risk of glioma, while polymorphisms rs1136410 (OR = 0.78 (0.68-0.89), P = .0004)...

Association of ERCC1 and ERCC2 polymorphisms with colorectal cancer risk in a...

Ni(Min),Zhang(Wei-zhong),Qiu(Jin-rong),Liu... Sci Rep 2015-10-19

The ERCC1 and ERCC2 genes are important in repairing DNA damage and genomic instability, and are involved in the nucleot...

[Study on the effect of deficient ERCC2/XPD gene on the repair of DNA damage ...

Guan(Yangyang),Xiao(Sha),Li(Dandan),Xue(Pi... Wei Sheng Yan Jiu 2015-03-30

...ERCC2/XPD defective, indicating us that ERCC2/XPD play a critical role in the repair process of DNA damage induced by UV...

Changes in the expression of DNA double strand break repair genes in primordi...

Govindaraj(Vijayakumar),Keralapura Basavar... Reprod Biomed Online 2015-12-03

...ERCC2 (P < 0.05), and H2AX (P < 0.01) of DNA repair genes and phospho-protein levels of BRAC1 (P < 0.01) and H2AX (P < 0...

Single nucleotide polymorphisms of nucleotide excision repair and homologous ...

Jin(Guojun),Wang(Min),Chen(Weida),Shi(Wei)... Pak J Med Sci 2015-06-23

...ERCC2 rs1799793 and rs13181, NBN rs709816 and rs1805794, RAD51 rs1801320, rs1801321 and rs12593359, and XRCC3 rs861539 w...

Beyond conventional chemotherapy: Emerging molecular targeted and immunothera...

Ikeda(Sadakatsu),Hansel(Donna E),Kurzrock(... Cancer Treat Rev 2015-11-06

...ERCC2, FGFR3, and HER2. Molecular targeted therapies against similar genetic alterations are currently available for oth...

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