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The USP46-MCM7-RAD51 axis confers oxaliplatin resistance in colon cancer by a...

Wu(C),Zhu(W),Liu(Z),Xiao(T),Zuo(C),Zhu(Z),... Acta Biochim Biophys Sin (S... 2026-06-25

...RAD51 expression and facilitates the assembly of RAD51 foci, thereby increasing homologous recombination repair (HRR) ca...

Pathogenic variants in the human TONSL protein associated with SPONASTRIME dy...

Karmakar(A),Roy(S) Sci Adv 2026-07-31

...RAD51 foci formation, and exhibit severely compromised survival following genotoxic stress. These findings establish TON...

Genomic profiling identifies actionable DNA-repair defects in a new cervical ...

Polten(R),Kutle(I),Stalp(JL),Hachenberg(J)... Sci Rep 2026-07-29

...RAD51 and MLH1 were among these actionable targets. The newly described cervical cancer model revealed sensitivity towar...

Bone marrow mesenchymal stem cell-derived CHI3L1 protected against Helicobact...

Qianqian(W),Xiaoxiao(W),Yongbin(W),Jing(C)... J Biol Chem 2026-08-07

...Rad51 expression and promoting cellular DNA repair. Meanwhile, untargeted metabolomics and lipidomics further demonstrat...

Navigating nuclear space: How Rad51 filaments promote long-range homology sea...

Lakhal(F),Taddei(A) DNA Repair (Amst) 2026-08-05

...Rad51-mediated homology search. This review synthesizes recent advances in our understanding of HR, with a focus on the ...

TRIM28 regulate G2/M transition via histone modification and DNA damage repai...

Ma(RJ),Tang(MM),Lu(PS),Zhang(HL),Ju(JQ),Wa... J Cell Sci 2026-08-10

...RAD51, which were collectively contributed to GVBD failure in mouse oocytes. In conclusion, our findings indicate that T...

Nucleostemin promotes RAD51 filament assembly on double-stranded DNA to prote...

Chang(CC),Tsai(SS),Chou(CL),Chang(YH),Hung... Nucleic Acids Res 2026-08-10

...RAD51 foci formation and unleashing MRE11-mediated degradation. Through biochemical reconstitution and single-molecule f...

The tumor suppressor menin is a key scaffold mediator for homologous recombin...

Lian(A),Zhu(X),Jin(B),Gu(G),Xu(B),Zhang(L)... Nucleic Acids Res 2026-08-10

...Rad51 pathway. Restoring H3K36me3 via pharmacological intervention rescued impaired HR repair in Men1-deficient cells, f...

Risk stratification and multi-omics reveal RAD51 inhibition as a radiosensiti...

An(R),Li(J),Liu(T),Tang(C),Lu(H) Front Immunol None

...RAD51 as a core biological dependency. Importantly, RAD51 knockdown sensitized TNBC cells to irradiation by exacerbating...

Genome-scale CRISPR screening uncovers SRSF6 as a target to sensitize hepatoc...

Jiang(W),Sui(X),Dong(D),Jiang(L),Zheng(X),... JHEP Rep 2026-08-12

...RAD51 overexpression rescue assays were performed. The therapeutic potential of the SRSF6 inhibitor indacaterol was eval...

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