文献库搜索 | GeneLibs

Aoki(T),Inui(A),Ogata(Y),Igarashi(A),Yanag... J Hum Genet 2026-01-00

Rad50-interacting protein (RINT1) interacts with the endoplasmic reticulum (ER) tethering and SNARE complex, playing a c...

DeFoer(MB),Mostafa(AM),Hartlerode(AJ),Orba... bioRxiv 2025-07-18

...RAD50/NBS1 (MRN) complex. MRN localizes to chromosomal DSBs and recruits and activates the apical DSB repair protein kin...

Vigneswaran(A),Shi(K),Aihara(H),Evans(RL),... Acta Crystallogr F Struct B... 2025-09-01

...RAD50-NBS1/Xrs2 (MRN/X) protein complex acts as a first responder in DNA double-strand break repair and telomere-length ...

Hohl(M),Yu(Y),Kuryavyi(V),Patel(DJ),Petrin... Nat Commun 2025-08-12

...Rad50 and Nbs1 (Xrs2 in S. cerevisiae). The core components, Mre11 and Rad50 are highly conserved, with readily identifi...

Sailer(AL),Wörtz(J),Smith(V),Stachler(AE),... Microlife 2025-00-00

...Rad50, Fen1, PolB1, LigA, and LigN take part in MMEJ, as previously inferred. In addition, we show that Cas1 and Hel308a...

Gao(T),Zheng(Y),Zhang(B),Cao(P),Zhang(H),W... Int J Biol Macromol 2025-08-00

...Rad50 to drive DSB repair via homologous recombination. While Mre11's dual enzymatic activities (3' → 5' exonuclease and...

Lee(Y),Kim(HD),Lee(SY),Lee(H),Hyung(J),Moo... Gastric Cancer 2025-11-00

...RAD50, RAD51, RAD51C, RAD51D, RAD52, RAD54L, and XRCC2) was assessed using targeted next-generation sequencing. Among pa...

Belmonte-Fernández(A),Herrero-Ruíz(J),Sáez... Commun Biol 2025-07-11

...RAD50, is among the earliest elements involved in detecting DNA damage. Upon detecting DNA breaks, this complex triggers...

Vigneswaran(A),Canny(MD),Azatian(SB),Latha... J Mol Biol 2025-12-01

The MRE11-RAD50-NBS1/Xrs2 (MRN/X) complex is a conserved first responder to DNA double-strand breaks (DSBs). All three m...

Oyama(S),Matsuda(A),Murakami(R),Kakizaki(Y... Sci Rep 2025-07-03

...RAD50 have been identified as genes associated with gemcitabine resistance. Additionally, SLC25A10 and MAP3K9 were ident...