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Matrine targets Enolase 1 and regulates the glycolysis-lactylation axis to en...

Lin(L),Xia(M),Liang(R),Zhu(M),Chen(X),Zhan... Phytomedicine 2026-09-00

...RAD50-MRE11 DNA repair complex and downregulated resistance-associated transcription factors YY1 and YBX1. Importantly, ...

Uncovering Hereditary Risk: Germline Homologous Recombination Repair Variant ...

Kapoor(A),Uthale(S),Chain(A),Rungta(A),Ano... JCO Glob Oncol 2026-08-00

...RAD50, NBN, MRE11, and FANCC. Of 950 patients analyzed, 364 (38.3%) harbored variants in HRR genes, with 266 (28%) carry...

Genomic Alterations and Their Clinical Implications in Pancreatic Ductal Aden...

Dong(M),Hua(J),Ma(Z),Tang(R),Wei(M),Lv(Z),... Cancer Med 2026-07-00

...RAD50 p.L719fs, ATR p.I774fs, and germline RAD51D p.K91fs were homologous recombination repair (HRR) gene mutations enri...

Analysis of Migration and Adaptive Evolution in Tibetan Sheep Populations.

Zhang(W),Yuan(C),Guo(T),Chen(B),Wang(F),Li... Animals (Basel) 2026-01-20

...RAD50 [RAD50 Double Strand Break Repair Protein]). These genes are associated with adaptation to hypoxia and intense UV ...

MRE11 deacetylation by SIRT2 promotes DNA binding to facilitate DNA end resec...

Sesay(F),Zhang(H),Kapoor-Vazirani(P),Jung(... J Clin Invest 2026-03-02

MRE11, a breast tumor suppressor and component of the MRE11-RAD50-NBS1 complex, plays a critical role in DNA end resecti...

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing ...

Mack(M),Tufino(AC),Jamalruddin(MA),Dey(S),... Pediatr Blood Cancer 2026-03-00

...RAD50 in a patient with a rare prostate primary EwS and later concurrent relapsed EwS and therapy-related acute myeloid ...

CRISPR-Cas targeting in Haloferax volcanii promotes within-species gene excha...

Choudhary(DK),Turgeman-Grott(I),Robinzon(S... Microlife None

...Rad50 complex, which are known to have elevated recombination activity, also exhibited higher mating success. Indeed, th...

NRZ complex facilitates virus infection via enhancing ER-LD contacts.

Li(Z),Xing(Y),Huang(X),Tian(B),Mei(J),Fu(X... J Cell Biol 2026-03-02

...RAD50 interactor 1 (RINT1) and zeste white 10 (ZW10), is essential for HCV-induced ER-LD association and viral infection...

The inhibition of the MRN complex by Mirin radiosensitizes particularly HPV-n...

Hildebrand(LS),Mehravani(BP),Khalifa(M),Sc... Cancer Cell Int 2026-02-04

...Rad50-Nbs1 (MRN) inhibitor Mirin with ionizing radiation (IR). Our hypothesis is that the inhibition of the cancer cells...

Development and validation of gene expression-based signature for high-grade ...

Vaicekauskaitė(I),Juodakis(J),Kazlauskaitė... J Ovarian Res 2026-01-27

...RAD50, PPT2, LUC7L2, PKP3, CDCA5, ZFPL1, VPS33B, GRB7, and TCEAL4) was selected for further analysis in the external coh...

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