Hammer(Eva),Heilbronn(Regine),Weger(Stefan... FEBS Lett 2008-02-04

Human Topors has originally been identified as binding partner of p53 and DNA topoisomerase I (TOP1). It can function as...

Chakarova(Christina F),Papaioannou(Myrto G... Am J Hum Genet 2007-11-27

We report mutations in the gene for topoisomerase I-binding RS protein (TOPORS) in patients with autosomal dominant reti...

Pungaliya(Pooja),Kulkarni(Diptee),Park(Hye... J Proteome Res 2007-11-21

...TOPORS. These findings suggest that TOPORS may function as a tumor suppressor by regulating mSin3A and other proteins in...

Yao(Zhan),Duan(Shanshan),Hou(Dezhi),Heese(... EMBO J 2007-04-05

...TOPORS, a p53 and topoisomerase I binding protein, and possibly displaces p53 from TOPORS, allowing p53 to stimulate cas...

Lemos(Taíla A),Kobarg(Jörg) Cell Biochem Biophys 2006-08-24

...Topors), HPC2, UBA2, TDG, and protein inhibitor of activated STAT (signal transducer and activator of transcription) (PI...

Whitelaw(William) Adv Exp Med Biol 2006-12-12

At altitude normal people often develop periodic breathing in sleep--regularly recurring periods of hyperpnea and apnea....

Lin(Ling),Ozaki(Toshinori),Takada(Yuki),Ka... Oncogene 2005-06-03

...topors exhibits extensive similarity to human topors. Overexpressed myc-tagged topors associates with and stabilizes p53...

Shinbo(Yumi),Taira(Takahiro),Niki(Takeshi)... Int J Oncol 2005-06-17

...Topors/p53BP3, a ring finger protein binding to both topoisomerase I and p53, in vitro and in vivo and that both protein...

Weger(Stefan),Hammer(Eva),Heilbronn(Regine... FEBS Lett 2005-10-25

...Topors SUMO-1 E3 ligase activity does not depend upon its RING finger motif. In HeLa cells, Topors induced p53 sumoylati...

Bredel(Markus),Bredel(Claudia),Juric(Dejan... Cancer Res 2005-07-07

...TOPORS, FANCG, RAD51, TP53BP1, and BIK) that could have a role in gliomagenesis.