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ISGylation of γH2AX retains MDC1 and facilitates homologous recombination rep...

Ghosh(A),Ray(P),Thomas(D),Jeeyar(V),Pillai... J Biol Chem 2026-05-00

...RAD51 foci formation at damage sites. Using a tissue microarray of chemoresistant EAC patients, we observed that ISG15 i...

MDS/AML-associated DDX41 helicase facilitates homologous recombination repair...

Aggarwal(A),Yang(S),Winstone(L),Mondal(S),... Nucleic Acids Res 2026-02-24

...RAD51 foci were found in DDX41 KO and DDX41-R525H expressing cells, indicating a defect in the transition from end resec...

Boronophenylalanine-Mediated Boron Neutron Capture Therapy Confers Selective ...

Zhang(L),Quan(R),Huang(H),Wu(M),Wang(W),Zh... Cancer Biother Radiopharm 2026-03-12

...RAD51) and nonhomologous end joining (via KU70/80). This irreparable DNA damage resulted in G2/M phase arrest and activa...

BET inhibition disrupts the FOXM1-MYC axis to induce BRCAness and enhance PAR...

Fang(P),Saunders(A),Minn(K),Chua(KJ),Brook... NPJ Precis Oncol 2026-03-12

...RAD51 paralogs, suggesting a shared HR program. Functionally, transient knockdown of FOXM1 or MYC reduced BRCA1/RAD51 tr...

SERBP1 is required for efficient HR repair and cisplatin chemoresistance in l...

Xie(Y),Chen(Q),Tang(N),Zeng(Y),Zhao(J),Yan... Cell Death Discov 2026-03-19

...RAD51. Importantly, BRCA1 knockdown attenuated SERBP1-driven cisplatin resistance both in vitro and in vivo, establishin...

Astragalus small molecules protect BMSCs from radiation-induced bystander eff...

Miao(Z),Wu(M),Dai(S),Wang(X),Li(YY),Liu(F)... Front Oncol None

...RAD51 were abnormally activated in the adjacent BMSCs. However, after knockdown of IFT88 (SiIFT88), the protein expressi...

Phosphorylated DHX9 inhibited the progression of lung adenocarcinoma by regul...

Wu(L),Wang(S),Diao(X),Ma(X),Liu(Y) Int J Biol Markers 2026-03-20

...Rad51, pCtIP), EdU/CCK-8 (proliferation), TUNEL/flow cytometry (apoptosis), comet assay (DNA damage), CldU/IdU (replicat...

Replicative gaps in DNA damage tolerance, genome instability, and cancer ther...

Falbo(L),Costanzo(V) Mol Cell 2026-04-02

...RAD51/BRCA2-mediated stabilization, PCNA modifications, PARP1- and CTC1-STN1-TEN1 (CST)-dependent fill-in pathways, and ...

Role of Rab5b in the defense of Cynoglossus semilaevis against Vibrio vulnifi...

Han(T),Liu(Y),He(Z),Zhang(Y),Cao(W),Ren(J)... Int J Biol Macromol 2026-04-00

...rad51, etc.) and collaborates with AURKA for cell cycle progression. In vivo experiments demonstrated that Rab5b reduced...

Importin α characterizes a micronuclear environment associated with genomic i...

Miyamoto(Y),Kisanuki(R),Oshima(R),Yoshimur... J Cell Sci 2026-06-15

...RAD51, RPA2 and cGAS, showed mutually exclusive localization with importin α in MN, indicating that MN comprise function...

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