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Rad51 and RecA juxtapose dsDNA ends ready for DNA ligase-catalyzed end-joinin...

Konomura(Naoto),Arai(Naoto),Shinohara(Take... Nucleic Acids Res 0000-00-00

...Rad51 binds first to single-stranded (ss)DNA and then interacts with double-stranded (ds)DNA. However, when RecA or Rad5...

A second DNA binding site in human BRCA2 promotes homologous recombination.

von Nicolai(Catharina),Ehlén(Åsa),Martin(C... Nat Commun 0000-00-00

...RAD51 recombinase at DNA double-strand breaks. This function is executed by the C-terminal DNA binding domain (CTD) whic...

Recombination-independent recognition of DNA homology for repeat-induced poin...

Gladyshev(Eugene),Kleckner(Nancy) Curr Genet 0000-00-00

...Rad51 protein in this organism, consistent with a recombination-independent mechanism. Using an ultra-sensitive assay fo...

53BP1 ablation rescues genomic instability in mice expressing 'RING-less' BRCA1.

Li(Minxing),Cole(Francesca),Patel(Dharm S)... EMBO Rep 0000-00-00

...RAD51 foci form in cells expressing RING-less BRCA1 in response to DNA damage, but the cells nonetheless display the sub...

AXL Inhibition Suppresses the DNA Damage Response and Sensitizes Cells to PAR...

Balaji(Kavitha),Vijayaraghavan(Smruthi),Di... Mol Cancer Res 0000-00-00

...RAD51 foci formation. As a result, AXL inhibition caused a state of HR-deficiency in the cells, making them sensitive to...

Characterization of the recombination activities of the Entamoeba histolytica...

Kelso(Andrew A),Goodson(Steven D),Chavan(S... Mol Biochem Parasitol 0000-00-00

...Rad51 recombinase. Here, a biochemical characterization of highly purified ehRad51 protein is presented. The ehRad51 pro...

Pomegranate Intake Protects Against Genomic Instability Induced by Medical X-...

Nallanthighal(Sameera),Shirode(Amit B),Jud... Nutr Cancer 0000-00-00

...Rad51, Rad52 and Brca2) in the liver of PE-treated mice. Likewise, mRNA levels of antioxidant enzymes were reduced (Gpx1...

Cervantes and Quijote protect heterochromatin from aberrant recombination and...

Ryu(Taehyun),Bonner(Melissa R),Chiolo(Iren... Nucleus 0000-00-00

...Rad51 recruitment. Here we show that HR progression is initially blocked inside the heterochromatin domain by SUMOylatio...

Tyrosine phosphorylation stimulates activity of human RAD51 recombinase throu...

Subramanyam(Shyamal),Ismail(Mohammed),Bhat... Proc Natl Acad Sci U S A 0000-00-00

...RAD51 and properties of the RAD51 nucleoprotein filament. By mimicking RAD51 tyrosine phosphorylation with a nonnatural ...

Poly (ADP-ribose) polymerase inhibition synergizes with the NF-κB inhibitor D...

Lampiasi(Nadia),Umezawa(Kazuo),Montalto(Gi... Biochim Biophys Acta 0000-00-00

...Rad51 nuclear foci in Hep3B cells (not Huh7 cells), and silencing of Rad51 enhanced sensitivity of Huh7 cells to the DHM...

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