Chakarova(Christina F),Khanna(Hemant),Shah... Hum Mol Genet 2011-05-24

...TOPORS in the retina remain unknown. Here, we demonstrate that TOPORS is a novel component of the photoreceptor sensory ...

Renner(Florian),Moreno(Rita),Schmitz(M Lie... Mol Cell 2010-03-26

...TOPORS, which functions as a SUMO E3 ligase mediating SUMOylation of IKKepsilon at lysine 231. SUMO modification of IKKe...

Marshall(Henderson),Bhaumik(Mantu),Aviv(Ha... BMC Mol Biol 2010-06-22

...Topors as a tumor suppressor in various malignancies. To gain insight into the function of Topors, we generated a Topors...

Yang(Xiaoming),Li(Hongchang),Deng(Anping),... Mol Biol Rep 2010-10-25

...Topors is also involved in normal mitotic progression, since Topors depletion delays mitotic entry and affects mitotic p...

Selmer(Kaja Kristine),Grøndahl(Jan),Riise(... Acta Ophthalmol 2010-08-06

...TOPORS. This gene was sequenced in 19 family members and a novel missense mutation, c.1205a>c, resulting in an amino aci...

Park(Hye-Jin),Zheng(Haiyan),Kulkarni(Dipte... Biochemistry 2009-01-26

...TOPORS both in cells and in vitro. In addition, this mutation increased the binding of TOPORS to the E2 enzyme UbcH5a bo...

Yang(Xiaoming),Li(Hongchang),Zhou(Zinan),W... J Biol Chem 2009-09-01

...Topors), a p53-binding protein, as a Plk1 target. We show that Plk1 phosphorylates Topors on Ser(718) in vivo. Significa...

Schob(Claudia),Orth(Ulrike),Gal(Andreas),K... Ophthalmic Genet 2009-05-08

...TOPORS cause autosomal dominant retinitis pigmentosa (adRP). Examination of 160 adRP patients from continental Europe re...

Hammer(Eva),Heilbronn(Regine),Weger(Stefan... FEBS Lett 2008-02-04

Human Topors has originally been identified as binding partner of p53 and DNA topoisomerase I (TOP1). It can function as...

Guan(Bin),Pungaliya(Pooja),Li(Xiang),Uquil... J Biol Chem 2008-04-10

...TOPORS. NKX3.1 can be ubiquitinated by TOPORS in vitro and in vivo, and overexpression of TOPORS leads to NKX3.1 proteas...