...RAD51C interface within the BCDX2 complex as essential for regulating its ATPase activity. We hypothesize that, paradoxi...
...RAD51C [1]. The 23 patients with GPVs had 43 relatives eligible for cascade test and 22 non-eligible relatives (includin...
...RAD51C/PALB2 together, providing a plausible HR-inactivation mechanism for 71.4% of HRD tumors. Our modelled estimate of...
...RAD51C promoter methylation and HRD was assessed in 244 samples without a PV in HRR genes. BRCA1/RAD51C promoter methyla...
...RAD51C and the RNA helicase DDX21 as genes required for BPA resistance. Moreover, we show that BPA exposure increases th...
...RAD51C-RAD51D-XRCC2 (BCDX2), a key mediator of replication fork reversal. Using DNA fiber assays, we show that HELQ and ...
...RAD51C/D remained stable. PMS2 were more common than previously reported and declined with age (p = 0.03). Patients ≥70 ...
...RAD51C, BRIP1 (n = 1 each). Most patients undergoing genetic testing did not carry an inherited mutation; however, over ...
...RAD51C mutation. The patient declined treatment and genetic counseling, electing for palliative care. RAD51C plays a cri...
...RAD51C, XRCC3, RAD51D and XRCC2. Here, using cryo-electron microscopy, we find that the RAD51-XRCC3-RAD51C complex (RAD5...
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