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Prevalence of mutations in eyeGENE probands with a diagnosis of autosomal dom...

Sullivan(Lori S),Bowne(Sara J),Reeves(Meli... Invest Ophthalmol Vis Sci 2013-11-19

...TOPORS) were chosen for PCR-based dideoxy sequencing, along with the two X-linked RP genes, RPGR and RP2. RHO, PRPH2, PR...

UHRF2, a ubiquitin E3 ligase, acts as a small ubiquitin-like modifier E3 liga...

Oh(Yohan),Chung(Kwang Chul) J Biol Chem 2013-05-30

...TOPORS), TNF receptor-associated factor 7 (TRAF7), and tripartite motif containing 27 (TRIM27) have dual functions as ub...

Detection of novel mutations that cause autosomal dominant retinitis pigmento...

de Sousa Dias(Miguel),Hernan(Imma),Pascual... Mol Vis 2013-09-24

...TOPORS) commonly associated with autosomal dominant retinitis pigmentosa (adRP) that account for more than 95% of known ...

p28, a first in class peptide inhibitor of cop1 binding to p53.

Yamada(T),Christov(K),Shilkaitis(A),Brates... Br J Cancer 2013-09-10

...TOPORS, Pirh2 and HDM2 (human double minute 2) in p53wt and p53mut cells were in response to sustained increases in p53....

TOPORS modulates H2AX discriminating genotoxic stresses.

Seong(Ki Moon),Nam(Seon Young),Kim(Ji-Youn... J Biochem Mol Toxicol 2013-04-29

...TOPORS functions as a novel E3 ligase for H2AX ubiquitination. TOPORS was found to be dissociated from H2AX proteins whe...

Inhibition of PDGF-B induction and cell growth by syndecan-1 involves the ubi...

Braun(Kathleen R),DeWispelaere(Allison M),... PLoS One 2013-03-06

...Topors required for the interaction with the S1CD. By immunohistochemistry, Topors and Sdc-1 co-localized near the cell ...

Nuclear structure and chromosome segregation in Drosophila male meiosis depen...

Matsui(Maiko),Sharma(Krishn C),Cooke(Carol... Genetics 2012-03-01

...topors, the Drosophila homolog of the mammalian dual ubiquitin/small ubiquitin-related modifier (SUMO) ligase Topors. We...

Cell cycle and aging, morphogenesis, and response to stimuli genes are indivi...

Serão(Nicola V L),Delfino(Kristin R),South... BMC Med Genomics 2011-09-09

...Topors, Hras, Mdm2, Camk2g, Fstl1, Il13ra1, Mtap and Tp53 were associated with multiple survival events.Most genes (from...

Rapid decrease in active tension generated by C2C12 myotubes after terminatio...

Fujita(Hideaki),Hirano(Minoru),Shimizu(Kaz... J Muscle Res Cell Motil 2011-03-30

...Topors, and Cul2, were also changed after termination of artificial exercise. These results indicate that termination of...

Comprehensively surveying structure and function of RING domains from Drosoph...

Ying(Muying),Huang(Xiaotian),Zhao(Haijun),... PLoS One 2011-12-29

...Topors) and CG1134 (Mul1) in C3HC4, and CG3929 (Deltex) in C3H2C3 seem to display broader E2s binding profiles than othe...

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