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G quadruplex DNA facilitates a pervasive path to homologous recombination.

Thakur(BL),Basak(P),Khurana(S),Sharma(S),Lai… bioRxiv 2026-06-07

...RAD51AP1, WDR48, and USP1, and requires G4 motifs within the homologous repair template. DHX36 loss partially restores H...

ITGA5 promotes homologous recombination mediated radioresistance in esophageal …

Huang(X),Liu(J),Ren(J),Yuan(J),Huo(W),Zhang(… Oncogene 2026-09-04

...RAD51AP1. This signaling axis enhances homologous recombination repair efficiency by facilitating RAD51 chromatin loadin...

TERRA R-loops trigger a switch in telomere maintenance towards break-induced re…

In(S),Renck Nunes(P),Valador Fernandes(R),Li… EMBO J 2025-08-00

...RAD51AP1. TERRA R-loops interfere with semiconservative DNA replication, promoting telomere maintenance by a homology-di...

Phosphoregulation of RAD51AP1 function in homology-directed repair.

Sharma(N),Uhrig(M),Kwon(Y),Sung(P),Wiese(C) bioRxiv 2025-09-10

...RAD51AP1 or RAD51AP1-S277/282D. In cells, RAD51AP1-S277/282A confers no rescue of RAD51AP1 deficiency in toxicity tests ...

PTTG1IP Orchestrates Epithelial-Mesenchymal Transition and DNA Damage Response …

Zhang(H),Zhou(L),Wang(S),Yao(D),Ma(J),Hu(X),… Front Biosci (Landmark Ed) 2025-09-23

...RAD51AP1), and ATM serine/threonine kinase (ATM) promoters. Functionally, depletion of PTTG1IP led to increased radiatio...

Tensor GSVD of patient- and platform-matched tumor and normal DNA copy-number p…

Sankaranarayanan(Preethi),Schomay(Theodore E… PLoS One 2016-01-08

...RAD51AP1 and KRAS encode for human cell transformation, and are correlated with a cell's immortality, and a patient's sh...

NUCKS1 is a novel RAD51AP1 paralog important for homologous recombination and g…

Parplys(Ann C),Zhao(Weixing),Sharma(Neelam),… Nucleic Acids Res 2016-03-29

...RAD51AP1, but binds to DNA with reduced affinity when compared to RAD51AP1. Our results show that NUCKS1 is a chromatin-...

ATR inhibition rewires cellular signaling networks induced by replication stres…

Wagner(Sebastian A),Oehler(Hannah),Voigt(And… Proteomics 2016-10-26

...RAD51AP1, and PSMD4. We establish that ATR inhibition rewires cellular signaling networks induced by replication stress ...

RAD51AP1-deficiency in vertebrate cells impairs DNA replication.

Parplys(Ann C),Kratz(Katja),Speed(Michael C)… DNA Repair (Amst) 2015-10-19

...RAD51AP1, but not of HsRAD51AP1 is able to fully complement in cell survival assays. Notably, in RAD51AP1-deficient DT40...

Identifying microRNA/mRNA dysregulations in ovarian cancer.

Miles(Gregory D),Seiler(Michael),Rodriguez(L… BMC Res Notes 2013-02-27

...RAD51AP1 was found to be strongly anti-correlated with the expression of hsa-miR-140-3p, which was significantly down-re...

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