...RAD51 to compromise homologous recombination and induce parthanatos. These findings uncover a lipid-mediated vulnerabili...
...RAD51 inhibitor RAD51-IN-1, which outperformed the Notch inhibitor FLI-06 in resistant patient-derived organoids. Mechan...
...RAD51 to engage homologous recombination (HR)-mediated DNA damage repair to confer resistance of GSCs to IR. Importantly...
...Rad51 after DNA damage induced by camptothecin. These findings identify KDM8 as a key player in DSB repair, specifically...
...RAD51, respectively. These findings emphasize the complex role of miRNAs in ther-apy, highlighting their potential as bo...
...RAD51-DNA filaments, inhibits RAD51 ATPase activity, and promotes strand invasion, D-loop formation and strand exchange....
...RAD51 to DNA double strand breaks (DSBs) during HRR, though the magnitude of this defect in human cells is not entirely ...
...RAD51, a core enzyme of the homologous recombination (HR) pathway. This led to DNA double-stranded break accumulation, d...
...RAD51, CtIP, and CHK1. Further analysis identifies WDR5 as a DCAF protein that facilitates Cul4A-mediated proteolysis of...
...RAD51 recombinase in chromatin. Our data identify nascent strand gaps that are induced by olaparib independently of repl...
山东省济南市章丘区文博路2号
齐鲁师范学院 genelibs生信实验室
山东省济南市高新区舜华路750号
大学科技园北区F座4单元2楼
电话: 0531-88819269