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Comprehensive Genomic Profiling Reveals the Mutational Spectrum and Clinical ...

Ammous-Boukhris(N),Abdelmaksoud-Dammak(R),... Cancers (Basel) 2026-08-29

...RAD50 (n = 2 cases each), and MUTYH, BARD1, and BRIP1 (one case each). Furthermore, 56 VUS were identified; among them, ...

The 1H, 15N and 13C backbone resonance assignments of an intrinsically disord...

Dinh(HH),Jasper(AM),Baudin(A),Sung(P),Libi... Biomol NMR Assign 2026-09-04

...RAD50, RAD51, MYC, and RB. Here, we report the backbone resonance assignments of a BRCA1 IDR construct spanning residues...

Pharmacologic inhibition of RBBP4/p300-mediated homologous recombination acti...

Mapunda(JA),Laverty(DJ),Aziz(F),Le(A),Sang... Neurooncol Adv None

...RAD50, BRCA1, BARD1, BRIP1, and FIGNL1), with RAD51 and BRIP1 correlating strongly with RBBP4 and p300. Silencing RBBP4 ...

Insights into the function and structure of the R2TP (RUVBL1-RUVBL2-RPAP3-PIH...

Mohamed(M),Wu(R),Houry(WA) Cell Stress Chaperones 2026-07-00

...RAD50-NBS1 (MRN) complex. Additionally, the role of R2TP in ciliogenesis, circadian rhythm regulation, and transcription...

AI-based pathomics model predicts regulatory T cell infiltration and radiothe...

Peng(S),Chen(J),Wang(X),Wang(X),Yue(Q),Lan... Front Immunol None

...RAD50, suggesting a potential association with radiotherapy response. This AI-based pathomics framework offers a robust ...

Alternative Lengthening of Telomeres is dependent on RAD52 and RAD51 gene fun...

Itriago(H),Cohn(M) G3 (Bethesda) 2026-06-16

...RAD50 and RAD59 genes are not essential. This implies that the N. castellii ALT mechanism is dependent on homologous rec...

Causal Effects and Single-Cell Microenvironmental Implications of Germline Va...

Sheng(B),Wang(J) Hum Mutat None

...RAD50 that genetically predicted increased CRC risk. Single-cell analysis was subsequently performed to evaluate the cel...

D-Ribose-L-Cysteine mitigates copper-induced testicular toxicity in mice thro...

Omeiza(NA),Omeiza(FR),Chimezie(J),Ogunyemi... J Trace Elem Med Biol 2026-08-00

...RAD50), suggesting coordinated regulation of oxidative stress, inflammatory, apoptotic, and DNA repair pathways. Taken t...

Multifaceted roles of PDS5B in RAD51-dependent homology-directed DNA repair a...

Katz(JN),Samentar(L),Fang(Q),Ji(JH),Li(W),... Nat Commun 2026-05-20

...RAD50-NBS1. DNA binding activity resides within the disordered C-terminal region of PDS5B, and testing of a DNA binding ...

Rap1-mediated steric hindrance protects telomeres from MRX sensing.

Mattarocci(S),Reginato(G),Cannavo(E),Roisn... Nat Struct Mol Biol 2026-06-00

...Rad50-Xrs2NBS1 (MRXMRN) complex. The response to telomere length is thought to correlate with the number of DNA-bound te...

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