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Hwang(S S),Jang(S W),Lee(K O),Kim(H S),Lee... Allergy 0000-00-00

...Rad50 hypersensitive site 6 (RHS6) in the Th2 locus control region is essential for regulation of the Th2 cytokine genes...

Anand(Roopesh),Ranjha(Lepakshi),Cannavo(El... Mol Cell 0000-00-00

...RAD50-NBS1 (MRN) and CtIP proteins were implicated in the initiation of DNA end resection, but the underlying mechanism ...

Seeber(Andrew),Hegnauer(Anna Maria),Husted... Mol Cell 0000-00-00

The Mre11-Rad50-Xrs2 (MRX) complex is related to SMC complexes that form rings capable of holding two distinct DNA stran...

Kochańczyk(Tomasz),Nowakowski(Michał),Woje... Sci Rep 0000-00-00

...Rad50 zinc hook domain, which is highly conserved and facilitates the Zn-mediated homodimerization of Rad50 proteins. He...

Hoa(Nguyen Ngoc),Shimizu(Tsubasa),Zhou(Zho... Mol Cell 0000-00-00

...Rad50/Nbs1 complex initiates double-strand break repair by homologous recombination (HR). Loss of Mre11 or its nuclease ...

Deshpande(Rajashree A),Lee(Ji-Hoon),Arora(... Mol Cell 0000-00-00

The human Mre11/Rad50/Nbs1 (hMRN) complex is critical for the sensing, processing, and signaling of DNA double-strand br...

Durdíková(Kristína),Chovanec(Miroslav) Curr Genet 0000-00-00

...Rad50/Xrs2) and DNA ligase IV (Dnl4/Lif1). Mammalian NHEJ is more complex, primarily as a consequence of the fact that m...

Ye(Yanfang),Kirkham-McCarthy(Lucy),Lahue(R... DNA Repair (Amst) 0000-00-00

...Rad50. Mutation of all six lysine residues to arginine gave partial bypass of a sin3 HDAC mutant, suggesting that Rad50 ...

Johnson(Bryan A),Aloor(Heather L),Moody(Ca... Virology 0000-00-00

...Rad50, and NBS1, as well as the homologous recombination repair proteins BRCA1 and Rad51. Interestingly, we have found t...

Yan(R C),Wang(J),Huang(Z Z),Wang(Z Y),Wu(X... Zhonghua Er Bi Yan Hou Tou ... 0000-00-00

...Rad50-GFP carrying mutant Rad50 gene. The expressions of Mre11, Rad50, Nbs1, and relevant constituents composing MRN com...