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Women at high risk of breast cancer: Molecular characteristics, clinical pres...

Kleibl(Zdenek),Kristensen(Vessela N) Breast 0000-00-00

...RAD50, NBS1, BRIP1, FANCA, FANCC, FANCM, RAD51, RAD51B, RAD51C, RAD51D, and XRCC2 have been described as high- or modera...

RECQL4 Promotes DNA End Resection in Repair of DNA Double-Strand Breaks.

Lu(Huiming),Shamanna(Raghavendra A),Keijze... Cell Rep 0000-00-00

...RAD50-NBS1 (MRN), which senses DSBs and initiates DNA end resection with CtIP. The MRE11 exonuclease regulates the reten...

Ctp1-dependent clipping and resection of DNA double-strand breaks by Mre11 en...

Jensen(Kristi L),Russell(Paul) Nucleic Acids Res 0000-00-00

...Rad50-Nbs1 (MRN) endonuclease and Ctp1 (CtIP and Sae2 ortholog) are required for both activities in fission yeast but wh...

Expression of asthma susceptibility genes in bronchial epithelial cells and b...

Li(Xingnan),Hawkins(Gregory A),Moore(Wendy... J Asthma 0000-00-00

...RAD50-IL13 region, the expression levels of RAD50, not IL4, IL5, or IL13, were positively correlated between BEC and BAL...

Chromosomal Translocations in the Parasite Leishmania by a MRE11/RAD50-Indepe...

Laffitte(Marie-Claude N),Leprohon(Philippe... PLoS Genet 0000-00-00

...RAD50 was possible in a MRE11 null mutant that we had previously generated, providing good evidence that RAD50 may be di...

The Saccharomyces cerevisiae Mre11-Rad50-Xrs2 complex promotes trinucleotide ...

Ye(Yanfang),Kirkham-McCarthy(Lucy),Lahue(R... DNA Repair (Amst) 0000-00-00

...Rad50. Mutation of all six lysine residues to arginine gave partial bypass of a sin3 HDAC mutant, suggesting that Rad50 ...

Mre11 Is Essential for the Removal of Lethal Topoisomerase 2 Covalent Cleavag...

Hoa(Nguyen Ngoc),Shimizu(Tsubasa),Zhou(Zho... Mol Cell 0000-00-00

...Rad50/Nbs1 complex initiates double-strand break repair by homologous recombination (HR). Loss of Mre11 or its nuclease ...

Nbs1 Converts the Human Mre11/Rad50 Nuclease Complex into an Endo/Exonuclease...

Deshpande(Rajashree A),Lee(Ji-Hoon),Arora(... Mol Cell 0000-00-00

The human Mre11/Rad50/Nbs1 (hMRN) complex is critical for the sensing, processing, and signaling of DNA double-strand br...

Frequency of pathogenic germline mutation in CHEK2, PALB2, MRE11, and RAD50 i...

Kim(Haeyoung),Cho(Dae-Yeon),Choi(Doo Ho),O... Breast Cancer Res Treat 0000-00-00

...RAD50 c.1276C>T, and RAD50 c.3811_3813delGAA were newly identified in this study. A total of 15 missense variants were f...

Panel of SEREX-defined antigens for breast cancer autoantibodies profile dete...

Kostianets(Olga),Shyyan(Maksym),Antoniuk(S... Biomarkers 0000-00-00

...RAD50, PARD3, SPP1, SAP30BP, NY-BR-62 and NY-CO-58) was identified, which can differentiate breast cancer patients and h...

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