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Ekinci(B),Orenay-Boyacioglu(S),Erdogdu(IH)... Biomedicines 2026-02-25

...RAD50, BLM, NF1, AR, BRCA2, and KMT2C. Notably, PIK3CA mutations were significantly more frequent in geriatric patients ...

Bu(R),Haqawi(W),Razzaq(EAA),Azam(S),Iqbal(... Int J Mol Sci 2026-03-14

...RAD50, MSH6, POLD1 and NF1. Four patients (36.4%) carried PVs/LPVs in canonical FA pathway genes; this increased to five...

Tsyganov(MM),Bulatova(DZ),Fedorenko(AA),Lo... Curr Issues Mol Biol 2026-03-04

...Rad50, Rad51, Brca1, Brca2, and Pold4. Two genes, Rad52 and Bard1, exhibited increased expression levels. It was shown t...

Boutet(T),Sakr(R),Marzullo(M),Goyal(M),Cat... Nucleic Acids Res 2026-04-13

...Rad50-Nbs). Loss of Rad50 disrupts histone modification patterns and causes inappropriate reactivation of embryonic gene...

Huang(K),Brault(ME),Cong(K),Azazmeh(N),Col... Mol Cell 2026-05-21

...RAD50-NBS1 (MRN) complex levels, and phenocopies hypomorphic MRE11 mutations. MRE11pPAS-/- cells exhibit ectopic DNA rep...

Yang(C),Zheng(X),Sun(H),Du(J),Luo(Y),Wang(... J Biol Chem 2026-06-00

...RAD50, a key DNA repair gene. Post-transcriptional regulation led to an increase in RAD50 protein, which facilitated the...

Wang(X),Hua(WX),Liu(Y),Li(HD) Biol Direct 2026-04-03

...Rad50, NBS1, MRE11, XRCC1, LIG3, et al. Together, our findings suggest that miR-142-3p plays a radioresistant role in co...

Badakul(G),Maeda(J),Kato(TA) Front Oncol None

...RAD50-NBS1 (MRN) complex that senses DNA double-strand breaks (DSBs) and coordinates DNA damage response, including ATM ...

Chen(CH),Tsai(CW),Chang(WS),Lu(MK),Cho(DY)... Sci Rep 2026-03-11

...RAD50, and NBN, and PD risk, along with corresponding mRNA expression and DNA repair capacity. A total of 123 clinically...

Gopinathan(A),Jain(V),Sharma(D),Kumar(PRV) Sci Rep 2026-03-16

...RAD50, suggesting that HPRT mutation may influence DNA damage response pathways. Our findings indicate that chronic expo...