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Intratumoral plasma cells mediate CD8+ T cell infiltration and successful imm...

Lingo(JJ),Reis(R),Allamargot(C),Raygoza Ga... bioRxiv 2026-02-20

...natures prognose better patient survival. Plasma cells favorably remodel the tumor immune environment by increasing CD8+...

A Machine Learning and Benchmarking Approach for Molecular Formula Assignment...

Shabbir(B),Oliveira(PRB),Fernandez-Lima(F)... bioRxiv 2026-02-19

A machine learning approach to molecular formula assignment is crucial for unlocking the full potential of ultra-high re...

Structural modification of oxazolidinone antibiotics alters nascent peptide s...

Kleinman(JI),Raskar(T),Klepacki(D),Szal(T)... bioRxiv 2026-02-18

...nature of the amino acid at the penultimate position of the nascent peptide. It remains unknown whether this is a genera...

Discovery and dynamic pharmacology of μ-opioid receptor positive allosteric m...

O'Brien(ES),Wang(J),Tanguturi(P),Li(M),Whi... bioRxiv 2026-02-21

Opioid agonists such as morphine and fentanyl exert analgesic effects by binding and activating the μ-opioid receptor (μ...

Deep models of protein evolution in time generate realistic evolutionary traj...

Koehl(A),Prillo(S),Liu(M),Xiong(J),Weng(L)... bioRxiv 2026-02-20

...natures of natural evolution, including conservation patterns and family-specific dynamics. When simulating evolution al...

Deciphering epileptogenic and activity-dependent gene programs in the human b...

Lin(Q),Kang(C),Xavier(AM),Sanchez-Martin(I... bioRxiv 2026-02-18

...nature, cellular specificity, and pathological relevance of such programs in the human brain remain poorly understood. H...

Leveraging the dominant-negative effect of the kuru-protective G127V prion pr...

Gatdula(JRP),Orbe(IC),Tolton(SG),Saunders(... bioRxiv 2026-02-18

Prion diseases are fatal neurodegenerative disorders with no approved therapies that halt or reverse disease progression...

Reddit posts reveal how natural environments affect social anxiety in young p...

O'Connor(K),Hernandez(S),Schmidt(AL),Shire... medRxiv 2026-02-18

...nature-related posts through computational and manual review. The results showed a complex relationship between natural ...

Self-reported health history from 70,724 individuals reveals novel HLA associ...

Boquett(JA),Lin(SY),House(JS),Ahn(K),Susen... medRxiv 2026-02-19

...nature of their occurrence or general underreporting. Further, these studies have generally been conducted with HLA geno...

Herpes simplex virus genomes from an under-sampled population in Namibia reve...

Bowen(CD),Blake(A),Renner(DW),Hazel(MA),Ja... medRxiv 2026-02-19

Herpes simplex virus (HSV) is an endemic pathogen, infecting most adults world-wide. HSV infection can cause a wide spec...

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