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NCI-60 whole exome sequencing and pharmacological CellMiner analyses.

Reinhold(William C),Varma(Sudhir),Sousa(Fabr… PLoS One 2015-12-18

...RAD52, MTOR, STAT2 and TSC2 as well as a large number of candidate genes such as NOM1, TLL2, and XDH. We introduce two n...

Utilization of Rad51C promoter for transcriptional targeting of cancer cells.

Cao(Yan),Xu(Yan),Zhang(Lei),Li(Zhen),Jiang(Y… Oncotarget 2015-01-27

...Rad52 in a panel of normal and tumor cell lines. We found that Rad51C is significantly overexpressed in cancer cells. Th...

Fission yeast Rad52 phosphorylation restrains error prone recombination pathway…

Bellini(Angela),Girard(Pierre-Marie),Tessier… PLoS One 2015-05-29

...Rad52 leads to loss of the constitutive Rad52 phosphorylation observed in cells lacking Rad51 and to partial loss of Rad...

A RAD52 genetic variant located in a miRNA binding site is associated with glio…

Lu(Chao),Chen(Yi-Dong),Han(Sichong),Wei(Jiny… J Neurooncol 2015-12-01

...RAD52 single nucleotide polymorphisms (SNPs) have been identified previously, little was known on how the RAD52 SNPs are...

Genetic interactions among homologous recombination mutants in Candida albicans.

Bellido(Alberto),Andaluz(Encarnación),Gómez-… Fungal Genet Biol 2015-07-01

...rad52-ΔΔ rad59-ΔΔ compared to rad52-ΔΔ. Slow growth and decreased plating efficiency were caused, at least in part, by a...

Rad51 and Rad52 are involved in homologous recombination of replicating herpes …

Tang(Ka-Wei),Norberg(Peter),Holmudden(Martin… PLoS One 2015-08-18

...Rad52 recombinases in viral recombination was examined in human fibroblast cells 1BR.3.N (wild type) and in GM16097 with...

Multimerization domains are associated with apparent strand exchange activity i…

Chen(Chi-Fu),Brill(Steven J) DNA Repair (Amst) 2015-06-24

...Rad52 protein provided in vivo complementation, suggesting that multimerization is functionally important. An N-terminal...

Association of a functional RAD52 genetic variant locating in a miRNA binding s…

Li(Ziqiang),Guo(Yuan),Zhou(Liqing),Ge(Yunxia… Mol Carcinog 2015-11-03

...RAD52 plays a crucial part in maintaining genomic stability and prevent carcinogenesis. Several cancer susceptibility RA...

Tissue inhibitor of metalloproteinases-1 induces a pro-tumourigenic increase of…

Cui(H),Seubert(B),Stahl(E),Dietz(H),Reuning(… Oncogene 2015-09-29

...RAD52 and SDHD, were decreased in the presence of TIMP-1. Upon the overexpression of TIMP-1 in tumour cells, miR-210 was...

Screening of efficient siRNA target sites directed against gatekeeper genes for…

Ren(Jinghua),Lin(Jusheng),Dong(Xuyang),Xu(Do… J Huazhong Univ Sci Technolog… 2014-01-23

...Rad52, Ku70, Ku80) and screen the more effective target sites from candidates for further research, by using siRNA desig...

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